目的探讨松果体区结构在连续薄层冠状断面上形态结构的变化规律,为该区病变的影像学诊断和外科治疗提供解剖学依据。方法选择1例成人头部标本,应用冷冻数控铣削技术由前向后垂直于连合间线(AC-PC线)进行铣削。另选择健康成年男性10名,应用3D SPGR序列行与标本基线一致的3.0 T MR扫描。选取典型的断面标本图像与相应活体的MRI图像进行对照研究,探讨主要结构的变化规律。结果根据松果体柄的出现和松果体的消失,可将松果体区由前向后分为前、中、后3个部分,其形态由倒三角形向梯形、三角形依次过渡。在松果体区的前、中部内,第I间隙逐渐增大;至松果体区后部时则开始减小直至消失。大脑内静脉始终位于松果体区的中线上,其高度逐渐下降。结论应用冷冻数控铣削技术所获取的松果体区薄层断面标本图像,能清晰显示该区各结构的形态变化规律及与周围组织毗邻关系,为该区微小病变的影像诊断和外科治疗提供了详实的解剖学依据。
Objective To investigate the morphology and relationships with the adjacent structures in the pineal region on the thin sections and to provide anatomic data for imaging diagnosis and surgical treatment of diseases in this region. Methods By CT and MRI examination, one normal head specimen was selected for this study. Using the computerized freezing milling technique, the specimen was sliced from anterior to posterior. The in vivo MR images were obtained from ten normal Chinese male adult volunteers using a 3.0 T GE scanner. The base lines of the sectioning and the MR scan were perpendicular to the AC-PC line. Then primary sections were contrasted with the corresponding MR images. Results By the appearance of the pineal peduncle and the disappearance of the pineal gland, the pineal region could be divided into three parts from anterior to posterior, and the shape changed from an inverted triangle to a trapezoid and a triangle gradually. The first interspace was getting wider in the anterior and middle parts of the pineal region, while in the posterior part of the pineal region, it was getting nan~wer and disappeared finally. From anterior to posterior, the bilateral internal cerebral veins were always in the midline of the pineal region and descended gradually. Conclusion By the computerized freezing milling technique, the anatomic details and adjacent relationships of the pineal region could be exhibited clearly in the thin serial sections, which could help the imaging diagnosis and surgical treatments for minute diseases in this region.