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Cyclodextrin-Based Porous Nanocapsules
  • ISSN号:1001-604X
  • 期刊名称:Chinese Journal of Chemistry
  • 时间:2013.5.5
  • 页码:569-576
  • 分类:TQ658.41[化学工程—精细化工] TB383[一般工业技术—材料科学与工程]
  • 作者机构:[1]National Center for Nanoscience and Technology, Beijing 100190, China
  • 相关基金:The financial support of the National Science Foundation of China,the Ministry of Science and Technology of China (National Major Scientific Research Program,Grant No.2011CB932500) is acknowledged
  • 相关项目:基于石墨单层片的杂化多孔材料的制备
中文摘要:

Cyclodextrins (CD ) 被认为是一个种有点重要、有希望的 macrocyclic oligosaccharides,它包含能够招待各种各样的客人分子的恐水病的内部洞。CD 水溶性、无毒、商业地可得到以及便宜。因为这些有利特征, cyclodextrin 化学创造了盖住不同的地的很多有趣的工作,特别地基于 CD 的多孔的 nanocapsules (CDPNC ) 。化学 cross-linking 是开发准备 CDPNC 的一个重要方法。CDPNC 能被获得用不同跨连接器并且准备方法例如同类的方法, miniemulsion 聚合,和乳剂溶剂蒸发方法。因为 cross-linking,一个三维的网络被造它与 CD 的洞在 CDPNC 形成多孔的结构。归因于多孔的结构, CDPNC 在指向的分子的封装和可控制的版本的实现展出优秀表演,在象药交货系统和环境保护那样的应用程序显示有希望的前景。

英文摘要:

Cyclodextrins (CDs) are regarded as one kind of the most important and promising macrocyclic oligosaccha- rides, which contain hydrophobic internal cavities capable of hosting various guest molecules. CDs are water-solu- ble, non-toxic, commercially available as well as low-cost. Because of these favorable characteristics, cyclodextrin chemistry has created a great number of interesting works covering different fields, in particular CD-based porous nanocapsules (CDPNCs). Chemical cross-linking is an important way developed to prepare CDPNCs. CDPNCs can be obtained using different cross-linkers and preparation methods, such as homogeneous method, miniemulsion po- lymerization, and emulsion-solvent evaporation method. Because of cross-linking, a three-dimensional network is built which forms the porous structure in CDPNCs with the cavities of CDs. Attributed to the porous structure, CDPNCs exhibit excellent performances in encapsulation of targeted molecules and realization of controllable re- lease, indicating a promising prospect in applications such as drug delivery systems and environment protection.

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期刊信息
  • 《中国化学:英文版》
  • 主管单位:
  • 主办单位:中国化学会
  • 主编:
  • 地址:上海市枫林路354号中科院上海有机化学研究所
  • 邮编:200032
  • 邮箱:
  • 电话:021-54925243
  • 国际标准刊号:ISSN:1001-604X
  • 国内统一刊号:ISSN:31-1547/O6
  • 邮发代号:4-646
  • 获奖情况:
  • 中国期刊方阵“双高”期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),荷兰文摘与引文数据库,美国科学引文索引(扩展库),日本日本科学技术振兴机构数据库,英国英国皇家化学学会文摘
  • 被引量:175