中文摘要：

目的：探讨三维超声参数对体外受精／卵胞质内单精子显微注射．胚胎移植（IVF／ICSI．ET）妊娠结局的预测价值。方法：回顾性分析697例行IVF／ICSI助孕患者hCG注射日子宫内膜及内膜下超声参数，根据临床妊娠与否分组，比较妊娠组与非妊娠组的资料，并进一步根据促排卵方案行分层分析，研究各项超声参数与妊娠结局的关联。结果：①妊娠组的年龄、不孕年限和IvF周期数显著低于非妊娠（P〈0．05），而妊娠组的子宫内膜厚度、内膜体积大于非妊娠组瞅0．05）。妊娠组螺旋动脉收缩期速度（Psv）和舒张末期速度（EDV）、内膜下1mm血流指数（F11、内膜下3mm的FI和血管血流指数（VFI）高于非妊娠组，差异均有统计学意义（P〈0．05）。②超声参数与长方案患者妊娠结局无明显关联，而在短方案促排卵患者中，妊娠组和非妊娠组的内膜厚度及螺旋动脉EDV存在统计学差异（P〈0．05）。③Logistic回归显示周期数和内膜厚度可作为短方案患者妊娠结局的预测指标，受试者工作特征（ROC）曲线分析也提示内膜厚度对妊娠具有一定的预测价值。结论：IVF／ICSI患者hCG注射日子宫内膜和内膜下三维超声参数对妊娠结局的预测价值十分有限，内膜厚度对短方案患者妊娠具有一定的预测作用。

英文摘要：

Objective： To investigate the predicton value of parameters by three-dimensional ultrasound on pregnancy outcome during in vitro fertilization/intracytoplasmic sperm injection-embryo transfer （IVF/ ICSI-ET）. Methods： Ultrasound parameters of 697 patients measured on hCG injection day were retrospectively analyzed. These variables were compared between pregnant and non-pregnant patients. Stratified analysis was then conducted according to the controlled ovarianhyperstimulation （COH） protocol. Results： Compared with non- pregnant patients, pregnant women exhibited significantly lower age, infertility duration, IVF cycle and higher endometrial thickness, endometrial volume, endometrial spiral arteries peak systolic velocity （PSV）, end dias- tolic velocity （EDV）, subendometrial flow index （FI） and vascular flow index （VFI）. There were significant differences in endometrial thickness and EDV between pregnant and non-pregnant women who were treated with short protocol. Logistic analysis showed that IVF cycle and endometrial thickness could predict the pregnancy outcome of patients treated with short protocol. Receiver operating characteristic （ROC） curve analysis was also conducted to evaluate the predictive value ofendometrial thickness on pregnancy outcome. Conclusion： Three- dimensional ultrasound measurement on hCG injection day does not play an important role in the prediction of pregnancy outcome during IVF/ICSI-ET, while endometrial thickness correlates with pregnancy outcome of patients treated with short protocol.