失眠是肿瘤患者高发的临床症状,它增加了肿瘤患者的症状负担,严重影响患者的生活质量。但是与其他肿瘤相关的症候相比,它并没有得到足够的重视,缺少统一的治疗指南。本文对现有的关于肿瘤相关性失眠(cancer-related Insomnia,CRI)的研究进行回顾,从CRI的定义及病因、临床筛查、药物及非药物干预措施等方面阐述了现有研究的利弊,重点结合中医经典及文献研究总结了中医药治疗CRI的理论依据,整理了现有的中医药治疗CRI的临床研究。综合来看,CRI的有效干预措施不足,需要基础和临床进一步的研究。
Insomnia is highly prevalent in cancer patients. Insomnia increases cancer symptom burden and impairs quality of life. However,it has not gained as much attention as other cancer symptoms,and lack of standard treatment guidelines. This paper reviews the current researches from the aspects of definition and etiology,clinical screening,pharmacotherapy and non-pharmacotherapy interventions. Based on the classics of Traditional Chinese Medicine( TCM) and document researchprogress,we summary the theoretical basis of TCM for CRI. In conclusion,we lack the efficient interventions for CRI,more preclinical and clinical researches are needed.