中文摘要：

目的评估癫痫患儿卡马西平（CBZ）疗效与依从性的关系。方法通过查阅病历、问卷调查等方式,对2008年1月至今在我院门诊、病房首诊的癫痫患儿383例进行分析,评价CBZ治疗依从性与疗效的关系。结果 CBZ治疗依从性与疗效相关,规律服药和复查的癫痫患儿疗效显著升高（P＆lt;0.05）;治疗时间延长,CBZ治疗依从性降低;血药浓度监测可提高CBZ治疗依从性,CBZ浓度在治疗窗内的癫痫患儿依从性较高。结论癫痫患儿CBZ疗效与依从性密切相关。

英文摘要：

Objective To evaluate the correlation between adherence of children epilepsy patients and effect of carbamazeping（CBZ）,and analyze the main reasons.Methods By looking up medical records,sending out questionnaires,and et al,383 children epilepsy patients were enrolled in our study from Jan 2008 till now.Using retrospective method,the correlation between adherence of children epilepsy patients and effect of CBZ were analyzed.Results There is a significant correlation between adherence of children epilepsy patients and effect of CBZ.Compared with those who don＇t take CBZ and re-check regularly,children epilepsy patients who take CBZ and re-check regularly have significant better result（P0.05）.When duration is longer,adherence of children epilepsy patients is decreased.Adherence of children epilepsy patients is increased in those who take therapeutic drug monitoring.Conclusion Effect of CBZ has a significant correlation with adherence of children epilepsy patients.Clinical pharmacists could help parents of children epilepsy patient improve their recognition,boost the effect of CBZ in children epilepsy patients.