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青少年颅内动脉瘤的影像学特征及治疗
  • ISSN号:1672-5921
  • 期刊名称:中国脑血管病杂志
  • 时间:0
  • 页码:306-310
  • 语言:中文
  • 分类:R739.41[医药卫生—肿瘤;医药卫生—临床医学]
  • 作者机构:[1]首都医科大学宣武医院神经外科,北京100053
  • 相关基金:国家自然科学基金资助项目(30500519)
  • 相关项目:脊髓血管畸形静脉高压的致病机制及干预措施的研究
中文摘要:

目的探讨青少年颅内动脉瘤的影像学特征及治疗策略。方法对16例青少年(年龄为15—18岁;男10例,女6例)颅内动脉瘤的影像学特征、治疗方式及其结果进行回顾性分析。结果青少年颅内动脉瘤占同期颅内动脉瘤的0.9%。以蛛网膜下腔出血发病者8例,以肢体无力、动眼神经麻痹、外伤后鼻衄等发病者8例。共发现20个颅内动脉瘤,其中位于前循环15个,位于后循环5个;动脉瘤的部位:大脑中动脉5个,基底动脉及海绵窦内各3个,后交通动脉、脉络膜前动脉、颈内动脉各2个,眼动脉、大脑后动脉及椎动脉各1个。动脉瘤的直径〈15mm者13个,≥15mm者7个,其中4个〉25mm,属于巨大动脉瘤。3例患者为多发动脉瘤。16例患者中,12例接受治疗:①介入治疗8例:其中5例行动脉瘤内栓塞术治疗,2例行载瘤动脉闭塞,1例海绵窦段颈内动脉假性动脉瘤行支架置入术;②显微外科手术治疗4例:其中2例行动脉瘤颈夹闭术,2例大脑中动脉复杂动脉瘤行颅内外动脉旁路移植后行动脉瘤孤立术。未治疗4例:1例治疗前载瘤动脉闭塞,动脉瘤自愈;术前动脉瘤再破裂死亡1例,2例因治疗风险巨大未行治疗。9例治疗患者经平均45个月的随访,均恢复良好(格拉斯哥预后量表评分为4~5分)结论①大脑中动脉是青少年颅内动脉瘤的好发部位;巨大型、外伤性、多发性、梭形动脉瘤比例较高;②青少年颅内动脉瘤治疗难度较大,部分病例需采用载瘤动脉闭塞或血管旁路移植术后孤立动脉瘤的方法进行治疗,预后较好;⑧青少年颅内动脉瘤的发病方式、影像学特征及治疗特点与儿童颅内动脉瘤相似,而与成人区别较大。

英文摘要:

Objective To investigate the imaging features and therapeutic strategies of intracranial aneurysms in adolescents. Methods The imaging features, therapeutic strategies, and the outcome were analyzed retrospectively in 16 adolescents ( 10 males and 6 females) with intracranial aneurysms. Results Intracranial aneurysms in adolescents accounted for 0.9% of intracranial aneurysms at the same age period. Eight patients had subarachnoid hemorrhage; 8 had limb weakness, oculomotor palsy, and epistaxis. A total of 20 intracranial aneurysms in the 16 patients were found, including 15 at the anterior circulation and 5 at the posterior circulation, of them 5 aneurysms at the middle cerebral artery, 3 patients each at basilar artery and cavernous sinus, 2 patients each at posterior communicating artery, anterior choroidal artery and internal carotid artery, and 1 patient each at ophthalmic artery, posterior cerebral artery and vertebral artery. The diameter of aneurysms were 〈 15 mm in 13 and ≥ 15 mm in 7 aneurysms, 4 were giant aneurysms ( 〉25 mm) , 3 patients had multiple aneurysms. 12 of the 16 patients received the following treatments: ① 8 patients were treated with interventional methods, 5 of them were treated with aneurysm embolization, 2 were treated with parent artery occlusion, and 1 patient with pseudoaneurysm in cavernous segment of internal carotid artery was treated with stentting; ② 4 patients were treated with microsurgery, 2 of them were treated with aneurysm neck clipping, and the other 2 patients with complex middle cerebral artery aneurysms were treated with aneurysm trapping after extracranial-intracranial arterial bypass ; ③ 4 patients were not treated, the parent artery was occluded in one patient before the treatment, and the aneurysm was obliterated itself, one patient died of aneurysm rerupture before treatment, 2 patients were not treated because of high risks of any treatment. 9 treated patients were followed up for an average of 45 months, and they all recovered well ( G

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期刊信息
  • 《中国脑血管病杂志》
  • 中国科技核心期刊
  • 主管单位:中华人民共和国计划生育委员会
  • 主办单位:中国医师协会 首都医科大学宣武医院
  • 主编:刘承基 凌锋
  • 地址:北京市长椿街45号
  • 邮编:100053
  • 邮箱:cjcvd@vip.163.com
  • 电话:010-83128791
  • 国际标准刊号:ISSN:1672-5921
  • 国内统一刊号:ISSN:11-5126/R
  • 邮发代号:80-155
  • 获奖情况:
  • 国内外数据库收录:
  • 俄罗斯文摘杂志,美国化学文摘(网络版),荷兰文摘与引文数据库,荷兰医学文摘,中国中国科技核心期刊,中国北大核心期刊(2014版)
  • 被引量:8160