水生动物双RNA病毒( Aquabirnavirus,ABV)隶属双RNA病毒科Birnaviridae,是一类可引起水生动物爆发传染性病毒病的病原,在世界范围内给水产养殖业造成了巨大损失,其代表种为传染性胰脏坏死病毒( Infectious Pancreatic Necrosis Virus,IPNV)。ABV的基因组包括两段分节的RNA,以负链RNA为模板进行病毒基因组复制,编码5种成熟的蛋白;本文结合ABV的功能基因、致病机理、诊断检测及免疫防治等近年研究的热点做一综述,以期为研究者提供参考。
Aèuabirnavirus( ABV),beLonging to Birnaviridae,is a serious pathogen of a contagious viraL disease of a-èuatic animaLs,which has brought great Losses for aèuacuLture worLdwide,and Infectious Pancreatic Necrosis Virus ( IPNV)is its representative species. Its genome contains two separated bi-strand RNA fragment,negative strand RNA are used as tempLate in the genome repLication process,and 5 poLypeptides are encoded in the infection cycLe. The research progress of ABV in gene function,infection mechanism,detection,and prevention technoLogy are re-viewed,which wouLd be heLpfuL for aèuacuLture practitioners and researchers.