具有独特立体结构的三萜化合物是一类重要的生物活性天然产物,在消炎、降血脂、保肝护肾、抗菌、抗肿瘤、抗真菌等方面有着重要药用价值。利用其独特手性结构、亲脂性、生物活性以及生物相容性等特性,设计合成新型功能分子,可作为药物载体,发挥其识别功能以及用于医用材料等方面具有重要的作用。本文介绍了近年来以三萜为骨架设计合成的新型功能分子在离子、分子识别和自组装性能方面研究现状及其潜在的应用前景。
Triterpenoids,which mainly comes from natural medicinal plants,is used for the treatment of anti-inflammation,anti-virus,anti-tumor,anti-bacteria and anti-fungal activities.Due to the characteristic stereostructure,hydrophobic property,biological activity and biocompatibility,to design and synthesize new functional molecules with triterpenoid chiral skeleton is significant in the potential drug delivery,molecular recognition and medicinal materials,etc.In this review,the recent development of the functional molecules containing triterpenoid units are briefly summarized in the bioactivities,recognition and self-assembly.