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H9N2 influenza virus in China: a cause of concern
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  • 分类:S855.3[农业科学—临床兽医学;农业科学—兽医学;农业科学—畜牧兽医] S852.659.4[农业科学—基础兽医学;农业科学—兽医学;农业科学—畜牧兽医]
  • 作者机构:[1]Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, College of Veterinary Medicine,China Agricultural University, Beijing 100083, China
  • 相关基金:This work was supported by the National Natural Science Founda- tion of China (Grant Nos. 31430086 and 31302102), the National Basic Research Program (973 Program) (No. 2011CB504702), grants from the Chang Jiang Scholars Program, and the National Science Fund for Distinguished Young Scholars (31025029).
中文摘要:

有鸟的流行性感冒病毒的最近的人的感染表明那个 H9N2 流行性感冒病毒是为感染人的 H7N9 和 H10N8 病毒的基因施主。在动物人接口的 H9N2 病毒的关键角色可能由于宽主人范围,在家禽的改编和哺乳动物、广泛的基因分类。作为在在中国的鸡的流行性感冒病毒的最流行的子类型, H9N2 也为家禽工业引起大经济损失,甚至在长期的种痘节目下面。H9N2 流行性感冒病毒的历史,传染病学,生物特征,和分子的决定因素在这份报纸被考察。H9N2 基因的贡献,特别 RNP 基因,到以后要调查的人需要的感染。

英文摘要:

The recent human infection with avian influenza virus revealed that H9N2 influenza virus is the gene donor for H7N9 and H10N8 viruses infecting humans. The crucial role of H9N2 viruses at the animal-human interface might be due to the wide host range, adaptation in both poultry and mammalian, and extensive gene reassortment. As the most prevalent subtype of influenza viruses in chickens in China, H9N2 also causes a great economic loss for the poultry industry, even under the long-term vaccination programs. The history, epidemiology, bio- logical characteristics, and molecular determinants of H9N2 influenza virus are reviewed in this paper. The contribution of H9N2 genes, especially RNP genes, to the infection of humans needs to be investigated in the future.

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