目的:应用双抗体一步夹心法酶联免疫吸附(ELISA)实验,研究EN对艾滋病(AIDS)病人细胞凋亡膜表面分子及其配体(FAS/FASL)的影响。方法:检测30例AIDS病人服用EN液前和服用4周后FAS/FASL的指标变化,分析AIDS病人肠道功能的变化情况。结果:AIDS病人应用EN治疗4周后FAS/FASL明显降低,与EN前比有显著性差异(P〈0.05)。结论:EN治疗对AIDS病人的FAS/FASL具有调节作用。
Objective: To observe the effect of enteral nutrition on intestinal barrier function in patients with AIDS by ELISA. Methods: The level of FAS/FASL was measured in AIDS patients before and 4 weeks after EN. Results : The intestinal barrier function in AIDS patients was improved after eating Enteral nutrition ( P 〈 0.05 ). Conclusion : Enteral nutrition has a regulatory role on FAS/ FASL in AIDS patients.