黄褐毛忍冬为忍冬属植物Lonicera fulvotomentosa Hsu et S.C.Cheng的干燥花蕾,系贵州省地方标准品种,并已被载入2005年版《中国药典》增补版,列为山银花药材基源植物之一.研究结果表明,黄褐毛忍冬总皂苷具有保肝和抗炎等活性,特别是对多种作用机制不同的化学毒物引起的肝损伤均有不同程度的保护作用.然而目前对其化学成分的研究尚不够深入,仅报道了黄褐毛忍冬皂苷甲、无患子皂苷B和α-常春藤皂苷等皂苷成分.
A new triterpenoid saponin was isolated from Lonicerafulvotomentosa. The structure of the new triterpenoid saponin, named Fulvotomentoside B, was elucidated as 3-O-β-D-xylopyranosyl (1→3)-α-L-rhamnopyranosyl ( 1 →2 ) -α-L-arabinopyranosyl hederagenin-28-O-β-D-xylopyranosyl ( 1 →6 ) -β-D-glucopyranosyl ester on the basis of spectroscopic analysis as well as chemical methods. In addition, the structure of Fulvotomentoside A, the previously reported major saponin, was revised, and it should be 3-O-β-D-xylopyranosyl ( 1→3 ) -α-L-rhamnopyranosyl ( 1 → 2 ) -α-L-arabinopyranosyl hederagenin-28-O-β-D-glucopyranosy ( 1 → 6 ) -β- D-glucopyranosyl ester( Decaisoside E) on the basis of careful analyses of new spectroscopical data.