位置：成果数据库 > 期刊 > 期刊详情页
聚乙二醇和叶酸对层状双金属氢氧化物颗粒的表面修饰
  • ISSN号：0251-0790
  • 期刊名称：高等学校化学学报
  • 时间：2013.6.20
  • 页码：596-600
  • 分类：O648[理学—物理化学;理学—化学]
  • 作者机构：[1]山东大学胶体与界面化学教育部重点实验室,济南250100, [2]山东大学物理学院,济南250100
  • 相关基金：国家自然科学基金（批准号：21173135,50972082）;高等学校博士学科点专项科研基金（批准号：20110131130008）资助
  • 相关项目：LDHs诱导双亲分子的自组装形成囊泡体系的研究
作者： 夏志勇, 杜娜, 刘建强, 侯万国*|
关键词： 层状双金属氢氧化物, 聚乙二醇, 叶酸, 表面修饰, 再分散性, Layer double hydroxide（LDH）, Poly（ethylene glycol）, Folic acid（FA）, Surface modification, Re-dispersibility
中文摘要：

以具有伪装隐形作用的聚乙二醇（PEG）和具有靶向作用的叶酸（FA）为修饰剂,以氨丙基三甲氧基硅烷（APTMS）为连接剂,对Mg3Al-NO3层状双金属氢氧化物（LDH）进行了表面修饰,制备了LDH-PEG-FA纳米颗粒,并通过X射线衍射（XRD）、透射电子显微镜（TEM）、紫外-可见光谱（UV-Vis）、傅里叶变换红外光谱（FTIR）、粒度分布分析和元素分析等技术对其结构进行了表征.结果表明,PEG和FA的修饰量可由其原料配比调控,修饰后的产物具有良好的水再分散性,这主要源于修饰层的空间位阻效应.预期LDH-PEG-FA同时具有伪装隐形性和靶向性,可用于药物载体等领域.

英文摘要：

Using（3-aminopropyl）trimethoxy silane（APTMS） as linker agent,the Mg3Al-NO3 layer double hydroxides（LDH） particles surface were modified by poly（ethylene glycol）（PEG） with disguise function and folic acid（FA） with targeted function.The obtained surface modified LDH particles（LDH-PEG-FA） were characterized by X-ray diffraction（XRD）,transmission electron microscope（TEM）,UV-Vis spectrometer,Fourier transform infrared spectrometer（FTIR）,laser particle size analyzer and elemental analysis（EA）,respectively.The results show that the surface modification of LDH particles can be controlled by the variation of the amount of PEG and FA used in raw materials.Particularly,the modified products exhibit good water re-dispersibility which is mainly attributed to the space steric effect of the modified layers.As the characteristic of disguising and targeting,the LDH-PEG-FA is expected to be used in drug delivery field.

同期刊论文项目
偶氮液晶插层类水滑石纳米复合材料的液晶性和磁性研究
期刊论文 13 会议论文 1
LDHs诱导双亲分子的自组装形成囊泡体系的研究
期刊论文 50
同项目期刊论文
Interaction between xanthan gum and cationic cellulose JR400 in aqueous solution
Rheological properties of aqueous solution containing xanthan gum and cationic cellulose JR400
A sorbent concentration-dependent Freundlich isotherm
Synthesis and characterization of 10-hydroxycamptothecin – sebacate – layered do
Surfactant-free microemulsion composed of oleic acid, n-propanol, and H2O
10-羟基喜树碱-癸二酸-LDH杂化物的制备及性能
Ionic liquid microemulsions of 1-butyl-3-methylimidazolium hexafluorophosphate, N,N-dimethylformamid
Facile synthesis of camptothecin intercalated layered double hydroxide nanohybrids via a coassembly
A hierarchical Co–Fe LDH rope-like nanostructure: facile preparation from hexagonal lyotropic liquid
Synthesis of magnetite-graphene oxide-layered double hydroxide composites and applications for the r
Synthesis and characterization of g-C3N4/Bi2MoO6 heterojunctions with enhanced visible light photoca
Sorption of Cr(VI) on Mg–Al–Fe Layered Double Hydroxides Synthesized by Mechanochemical Method
Synthesis of layered double hydroxide nanosheets by coprecipitation using a T-type microchannel reac
Synthesis, characterization and enhanced visible light photocatalytic activity of Bi2MoO6/Zn-Al laye
Facile fabrication of ibuprofen–LDH nanohybrids via a delamination/reassembling process
Synthesis of Mg-Al-Fe-NO3 layered double hydroxides via a mechano-hydrothermal route
Enhanced visible light photocatalytic activity of bismuth oxybromide lamellas with decreasing lamell
Solid effect in solvent extraction treatment of pre-treated oily sludge
Sorbent concentration effect on adsorption of methyl orange on chitosan beads in aqueous solutions
Rough glass surface-mediated formation of vesicles from lauryl sulfobetaine micellar solutions
Synthesis, characterization, and visible-light photocatalytic activity of BiOI hierarchical ？owerlik
Vesicles composed of one simple single-tailed surfactant
Mechano-hydrothermal synthesis of SDS intercalated LDH nanohybrids and their removal efficiency for
A Nonconventional Model of Protocell-like Vesicles: Anionic Clay Surface-Mediated Formation from a S
Rough glass surface-mediated transition of micelle-to-vesicle in sodium dodecylbenzenesulfonate solu
Synthesis and Characterization of Camptothecin/Graphene Oxide/Hydrotalcite-like Compounds Nanohybrid
Sorption of Cr(VI) on Mg-Al-Fe layered double hydroxides synthesized by a mechanochemical method
Mechano-hydrothermal synthesis of Mg2Al-NO3 layered double hydroxides
MgFe2O4@(替加氟-LDHs)磁性纳米复合体的制备及表征
Fe3O4@(TF-LDHs)纳米复合体的制备及药物缓释性能
Triton X-100六角液晶相中制备镁铝层状双金属氢氧化物纳米片及其药物载体应用
Nonaqueous ionic liquid microemulsions of 1-butyl-3-methylimidazolium tetrafluoroborate, toluene and
Mechano-hydrothermal synthesis of Mg2Al–NO3 layered double hydroxides
A Sorbent Concentration-Dependent Langmuir Isotherm
Mechanochemical synthesis of Fe3O4@(Mg-Al-OH LDH) magnetic composite
T形微反应器共沉淀法制备Mg-Al层状双金属氢氧化物及其粒径可控性
Facile synthesis of deoxycholate intercalated layered double hydroxide nanohybrids via a coassembly
剥离-共组装法制备葫芦素插层类水滑石纳米杂化物
喜树碱/氧化石墨烯/类水滑石纳米杂化物的制备及表征
Fe_3O_4@（TF-LDHs）纳米复合体的制备及药物缓释性能
一个与吸附剂浓度有关的Langmuir等温式
T形微反应器共沉淀法制备Mg—Al层状双金属氢氧化物及其粒径可控性
MgFe2O4@（TF-LDHs）磁性纳米复合体的制备与表征
环氧氯丙烷交联黄原胶溶液的流变及抗温性能
Synthesis and liquid crystal properties of a new organometallic palladium complex
染料插层类水滑石纳米复合材料的研究进展
Fabrication, characterization, and photocatalysis of GaN-Ga2O3 core-shell nanoparticles
Theoretical illustration on the catalytic effect of alanine methyl ester nitrate ionic liquid on the
Synthesis and characterization of nanosized zinc aluminate spinel from a novel Zn-Al layered double
Preparation of ZnAl2O4 spinel directly from zinc aluminum layered double hydroxide precursor
Structure and growth mechanism of quasi-aligned GaN layer-built nanotowers
有机无机杂化太阳能电池的研究进展
Effects of a reagent＇s rotational and vibrational excitations on reactionO(3P)＋ H2(ν=0, 3, j = 0, 3, 5, 7, 9, 12, 15) → OH ＋ H
期刊信息
  • 《高等学校化学学报》
  • 北大核心期刊（2011版）
  • 主管单位:中华人民共和国教育部
  • 主办单位:吉林大学 南开大学
  • 主编：周其凤
  • 地址：吉林大学南胡校区
  • 邮编：130012
  • 邮箱：cjcu@jlu.edu.cn
  • 电话：0431-88499216
  • 国际标准刊号：ISSN：0251-0790
  • 国内统一刊号：ISSN：22-1131/O6
  • 邮发代号:12-40
  • 获奖情况:
  • 首届及第二届国家期刊奖,连续两届“百种中国杰出学术期刊”,中国期刊方阵“双高”期刊
  • 国内外数据库收录:
  • 俄罗斯文摘杂志,美国化学文摘（网络版）,荷兰文摘与引文数据库,美国工程索引,美国科学引文索引（扩展库）,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊（2004版）,中国北大核心期刊（2008版）,中国北大核心期刊（2011版）,中国北大核心期刊（2014版）,英国英国皇家化学学会文摘,中国北大核心期刊（2000版）
  • 被引量:50676