中文摘要：

手性噁唑硼烷是不对称合成的重要催化剂，它可以高产率、高立体选择性地催化酮、内消旋酰亚胺以及亚胺的不对称还原，催化立体选择性Diels-Alder反应、不对称Mukaiyama缩合反应等重要有机化学反应．概述了近十年来手性噁唑硼烷在不对称合成中的研究进展以及在合成VB12等多种天然及非天然活性化合物中的应用．

英文摘要：

Chiral oxazaborolidines are very important catalysts for asymmetric reduction of ketone, cyclic meso-imides and imines as well as Mukaiyama aldol reaction and enantioselective Diels-Alder addition with excellent yield and enantioselectivity. Progress on the study of chiral oxazaborolidines and their application in synthesizing natural or non-natural products and biological active compounds including VB12 are reviewed.