中文摘要：

吲哚及其衍生物具有独特的生理活性，该文主要应用1DNMR和2DNMR技术（COSY，HSQC，HMBC，NOESY）对合成的吲哚衍生物的’HNMR、”CNMR谱信号进行了全归属．用变温NMR研究了N-叔丁氧羰基吲哚（化合物m）中c—N键的旋转受阻对氢谱和碳谱的影响，计算了融合温度下CN键旋转速率为175Hz，此温度下活化自由能为12kcal／m01．研究了化合物m的溶剂效应，发现在低极性溶剂中的C—N键的旋转阻力大于极性溶剂．

英文摘要：

1H and laC NMR signals of N-substituted indole derivatives were assigned u- sing 1D and 2D NMR techniques. The effects of C--N bond rotation barrier on the H and laC NMR signals in compound m was studied using variable-temperature NMR. Ro- tation rate and free energy were calculated under coalesce temperature. The rotation barrier dependence on the solvent effects of m was als0 studied. It was found that the rotation barrier about C--N in m was higher in polar solvent.