应用透射电子显微镜技术,对固始鸡17日龄胚胎、4周龄和19周龄固始鸡正常发育的中枢免疫器官超微结构进行了研究。结果表明,固始鸡胚胎胸腺和法氏囊超微结构不同于4周龄和19周龄固始鸡;在中枢免疫器官内免疫细胞存在着自然凋亡现象,主要表现为细胞核的变化,其次是线粒体增生。核质凝集为新月形、C字形、圆环形、花瓣状等多种形态,凋亡细胞裂解为凋亡小体,最后被巨噬细胞吞噬。
The ultrastructure of immune cells and natural apoptotic cells in central immune organs of Gushi chickens were studied by using transmission electronic microscopy technology. The results showed that the ultrastructure of immune cells in thymus and bursa was different between 17-day-embryo and 4-week and 19-week Gushi chickens. The natural apoptosis was found in central immune organs of Gushi chickens. The main changes of apoptotic cells appeared in nucleus. The proliferation of mitochondria happened in apoptotic cells. The chromatin were highly condensed. The C-shaped nucleus and crescent nucleus and petal-like nucleus and circle-shaped nucleus etc were observed. The apoptotic cells broke into many apoptotic bodies, which were phagocytosed by macrophages.