中文摘要：

为探索胸主动脉夹层发展与血液动力学因素的关系，借助计算流体动力学，对DeBakeym型胸主动脉夹层血液脉动流在正常血压和高血压下进行三维数值模拟，获得了夹层血液流动在一个心动周期内不同时刻真假腔纵向切面流线分布、真假腔入口横断面流线分布以及血管壁面压力和剪应力分布．计算结果表明，尽管血压值对血管壁面剪应力分布影响较小，但血压与真假腔内血液动力学行为密切相关；心缩期夹层假腔内压力远大于真腔内压力，夹层可能继续向下延伸发展．

英文摘要：

To discuss the relationship between the development of thoracic aortic dissection （TVD） and hemodynamics, three-dimensional simulation of blood flow in human DeBakey III type of TVD is investigated in normal and hypertension blood pressure using computational fluid dynamics. The pathline distributions on longitudinal section and cross-section of true and false lumens, wall pressure and wall shear stress for the blood flow of the TVD of DeBakey type m are obtained in a cardiac cycle. Numerical results show that the hemodynamic behaviors are closely related to the blood pressure, while the blood pressure has slight influence on the shear stress distribution. The blood pressure in true lumen is also larger than that in false lumen in systole, which suggests that the lumen may expand along the origin lumen.