中文摘要：

衣原体为完成发育周期以及逃避宿主免疫，进化形成一整套机制以实现持续性感染并对宿主细胞进行调控，抑制宿主细胞凋亡。细胞感染衣原体后，早期可以抑制Caspase酶系，抑制相关信号转导途径，且胞内线粒体发生一系列结构和功能的变化，抑制凋亡因子释放，一系列因子协同作用，抑制宿主细胞凋亡。本文从凋亡途径、凋亡蛋白、凋亡信号通路三个主要方面作了衣原体抑制宿主细胞凋亡机制概述，对进一步了解衣原体发育及其致病机制提供了新的研究思路。

英文摘要：

To ensure its long-term survival in the infected hosts and to escape from the efficient host immune mechanism, chlamydia has developed a set of mechanisms, so as to perform a productive infection and multi-regulation on host cell , and result in the inhibition of apoptosis for host cell.In the early infection by chlamydia, caspase activation and related sig-nal transduction pathway are inhibited, then a series of changes occurred in mitochondria structure and function, the release of apoptosis factors decreased, finally, host cell apoptosis is inhibited.This review describes three aspects of apoptosis in-cluding pathway, associated protein and signal pathway on the processes in chlamydia inhibition of host cell apoptosis, from, which the new ideas could be provided to further understand in development and pathogenesis of chlamydia.