中文摘要：

Three-dimensional imaging with single orientation is a potential and novel technique. We successfully demonstrate that three-dimensional(3D) structure can be determined by a single orientation diffraction measurement for a phase object of double-layer Mie-scattering silica spheres on a Si3N4 membrane. Coherent diffraction pattern at high numerical aperture was acquired with an optical laser, and the oversampled pattern was projected from a planar detector onto the Ewald sphere.The double-layered spheres are reconstructed from the spherical diffraction pattern and a 2D curvature-corrected pattern,which improve convergence speed and stability of reconstruction.

英文摘要：

Three-dimensional imaging with single orientation is a potential and novel technique. We successfully demonstrate that three-dimensional（3D） structure can be determined by a single orientation diffraction measurement for a phase object of double-layer Mie-scattering silica spheres on a Si3N4 membrane. Coherent diffraction pattern at high numerical aperture was acquired with an optical laser, and the oversampled pattern was projected from a planar detector onto the Ewald sphere.The double-layered spheres are reconstructed from the spherical diffraction pattern and a 2D curvature-corrected pattern,which improve convergence speed and stability of reconstruction.