目的:评估磁共振(MRI)和单光子发射计算机体层显像(SPECT)检测心肌缺血、坏死的价值。方法:冠心病拟行血运重建术患者28例,于术前1周内完成冠状动脉造影(CAG)、MRI和SPECT的对照检查,以CAG结果狭窄程度≥70%为标准,判断MRI和SPECT检出心肌缺血、坏死的敏感性、特异性和准确性。结果:CAG发现阳性血管共39支,阴性血管共45支。以CAG结果为标准,MRI检出心肌缺血的敏感度、特异度、准确度分别为92.31%、80.00%、85.71%,检出心肌坏死的敏感度、特异度、准确度分别为66.67%、91.11%、79.76%;SPECT检出心肌缺血的敏感度、特异度、准确度分别为94.87%、82.22%、88.10%,检出心肌坏死的敏感度、特异度、准确度分别为61.54%、86.67%、75.00%。统计学分析表明,MRI和SPECT显示缺血和坏死与CAG对照无明显差别,并且MRI和SPECT两种方法判断心肌缺血和坏死的准确度差异无明显统计学意义。结论:以CAG管腔狭窄程度≥70%为临界值,MRI与SPECT检出相应供血区心肌缺血、坏死的准确度较高,两者具有很好的一致性。
Objective:To assess the value of MRI and single photon emission computed tomography (SPECT) in detecting myocardial ischemia and necrosis. Methods.. Coronary angiography (CAG), MRI and SPECT were performed in 28 patients with coronary artery disease one week before revascularization operation. The stenosis criterion was a more than 70% stenosis by CAG; the sensitivity,specificity and accuracy of both MRI and SPECT were calculated according to the criterion. Results: CAG revealed 39 positive arteries and 45 negative arteries. According to the CAG results, the sensitivity, specificity and accuracy of MRI for detecting myocardial ischemia were 92.31%, 80.00% and 85.71%, respectively; and for detecting myocardial necrosis were 66.67%, 91.11%, and 79.76%, respectively. The sensitivity, specificity and accuracy of SPECT for detecting myocardial ischemia were 94.87%, 82.22% and 88.10%, respectively; and for detecting myocardial necrosis were 61.54%, 86.67%, and 75.00%, respectively. Conclusion: MRI and SPECT have high accuracy in detecting myocardial ischemia and necrosis and the results of the 2 methods accord well with each other.