随着免疫缺陷患者增多、器官移植和环境的日益恶化,真菌病的发生率正逐年上升,真菌的耐药性也日益严重,研究新型抗真菌药物和新的治疗途径已成为国内外研究的热点。对于真菌病的治疗,化学治疗是目前临床上的主要手段,而光动力治疗是新兴的方法。本文将从抗真菌的化学治疗药物和光动力治疗药物两个方面分析和总结抗真菌药物的研究现状和发展前景。
With the increasing in immunocompromised patients,organ transplanting and the environment deteriorating,the incidence of fungal disease has been increasing year by year,and the fungal drug resistance has become more and more serious.The studies of new antifungal drugs and new treatment approach have become a hot topic.For the treatment of fungal disease,chemotherapy is the primary clinical means,and photodynamic therapy is a new approach.In this paper,we will review the current status of the studies on antifungal chemotherapy and photodynamic therapy drug,and discuss their development prospects.