天然免疫通过细胞模式识别受体识别病原相关分子模式来清除感染。但是,在长期的进化过程中,许多病原体已经形成了自身的保护机制,从而逃逸天然免疫的杀伤。综述了模式识别受体介导的病原体的主要逃逸机制,以期为疾病的控制和预防提供新认识。
Innate immunity can clear the pathogen through the recognition of pathogen-associated molecular pattern recognition receptors (PRRs). But, in the long-time evolutionary process, many pathogens have developed some protective mechanisms to escape the killing of innate immunity. Here, we reviewed the research progress on escape mechanisms of patho~,ens mediated bv PRRs. in order to benefit the control and prevention of diseases.