中文摘要：

瞄准：在中国为严重尖锐胰腺炎(树液) 的早管理决定最划算的血过滤形式。方法：我们执行了 Pub-Medline 和中国生物医学的磁盘数据库的搜索。中国人口上的控制临床的试用在分析被包括。被分析的四个决定分支是：连续或长期的 veno 静脉的血过滤(CVVH/LVVH ) ，短期的 veno 静脉的血过滤(SVVH ) ， SVVH 正腹分离(PD ) ，和 non-hemofiltration 控制组。这种技术的有效性被幸存率，复杂并发症预防和外科保藏决定。住院的全部的费用也被估计。结果：SVVH 仅仅技术是最少的昂贵的形式， $5809 (44449 RMB ) ，并且作为基线治疗形式被选择。SVVH 仅仅手臂以全面幸存，复杂并发症预防和外科保藏完成了最低 C/E 比率。在增长划算分析， CVVH/LVVH 仅仅并且控制手臂低于另外的技术。敏感分析仅仅显示出 SVVH， SVVH 正 PD 手臂在 C/survival 比率重叠了。结论：为树液的其他的治疗仍然保持争论的早 veno 静脉的血过滤的角色。然而，我们建议短期的大量的 veno 静脉的血过滤的早使用将在树液的管理上有有益的影响。

英文摘要：

AIM： To determine the most cost-effective hemofiltration modality for early management of severe acute pancreatitis （SAP） in China. METHODS： We carried out a search of Pub-Medline and Chinese Biomedical Disk database. Controlled clinical trials on Chinese population were included in the analysis. The four decision branches that were analyzed were： continuous or long-term veno-venous hemofiltration （CVVH/LVVH）, short-term veno-venous hemofiltration （SVVH）, SVVH plus peritoneal dialysis （PD）, and non-hemofiltration control group. The effectiveness of the technique was determined by survival rate, complications prevention and surgery preservation. The total cost of hospitalization was also assessed. RESULTS： The SVVH only technique was the least costly modality, $5809 （44449 RMB）, and was selected as the baseline treatment modality. SVVH only arm achieved the lowest C/E ratio in terms of overall survival, complications prevention and surgery preservation. In incremental cost-effectiveness analysis, the CWH/ LVVH only and the control arms were inferior to other techniques. Sensitivity analysis showed SVVH only and SVVH plus PD arms overlapped in C/survival ratio. CONCLUSION： The role of early veno-venous hemofiltration as an alternative therapy for SAP remains controversial. However, we propose that early use of short-term high-volume veno-venous hemofiltration would have a beneficial impact on the management of SAP.