【目的】通过对肺热型变应性鼻炎过敏原的帕累托分析,探讨其规律,寻找肺热型变应性鼻炎发作的主要诱因,为肺热型变应性鼻炎的防治工作提供客观依据。【方法】采用前瞻性调查方法,对137例耳鼻喉科门诊肺热型变应性鼻炎患者进行血清特异性IgE阳性率、食物组及吸入组过敏原测定,并运用帕累托图分析找出最重要的过敏原。【结果】肺热型变应性鼻炎血清特异性IgE总阳性率为94.2%,主要过敏原食物组为鸡蛋(48.1%)、牛奶(24.8%)和虾(15.3%),吸入组为螨(40.9%),男性患者肺热型变应性鼻炎吸入组过敏原和女性患者肺热型变应性鼻炎吸入组过敏原差异无统计学意义(P〉0.05);女性患者食物组过敏原鸡蛋阳性率(58.8%)显著高于男性(37.7%),差异有统计学意义(P〈0.05),而牛奶和虾过敏男女患者差异无统计学意义(P〉0.05)。【结论】总体而言,肺热型变应性鼻炎的主要过敏原是尘螨和鸡蛋,次要过敏原是牛奶和虾,血清特异性IgE是诊断变应性鼻炎的敏感指标。
Objective Pareto analysis of allergens for lung-heat type allergic rhinitis was carried out for the exploration of its remote causes. Methods A prospective study was applied in lung-heat type allergic rhinitis outpatients adopted from December, 2010 to December, 2011 in otorhinolaryngology department. Serum specific IgE and allergens were detected in the patients. Pareto analysis was used for the screening of important food allergens or inhalation allergens in patients with positive serum specific IgE. Results The total positive rate for serum specific IgE was 94. 2% in the patients with lung-heat type allergic rhinitis. The main food allergens were eggs (48.1%), milk (24. 8% ) and shrimp ( 15.3% ), and the main inhalation allergen was acari (40. 9% ). The difference of inhalation allergen percentage was insignificant between the male patients and the female patients (P 〉0. 05). Female patients had higher egg-allergen positive rate (58.8%) than the male (37.7%), and the difference was significant ( P 〈 0. 05 ). However, the differences of milk-allergen positive rate and shrimp-allergen positive rate were insignificant (P 〉 0. 05 ). Conclusion In general words, acari and eggs are the predominant allergens for lung-heat type allergic rhinitis, and then come milk and shrimp. Serum specific IgE is one of the sensitive diagnostic indexes for allergic rhinitis.