中文摘要：

采用化学沉淀法合成了纳米羟基磷灰石粉体（HAP），以无水乙醇为沥滤剂，以16．7％（质量分数）的柠檬酸水溶液作粘结剂，通过粒子沥滤法制备了HAP／CMCS多孔材料，并对其进行了IR、XRD、SEM、孔隙率及抗压强度的测试。结果表明HAP／CMCS复合材料复合前后两组份的化学组成未发生显著变化，但两相间发生了相互作用。多孔材料孔隙率高，孔径分布范围宽，其尺寸分布大约从几微米到600微米，以圆形为主，具有良好的贯通性，非常有利于组织在其中的长入与扩展。当复合材料中CMCS含量为40％，复合材料／造孔剂的质量比为1：1时，多孔材料的孔隙率接近75％，其抗压强度可达21MPa以上，可以满足骨组织工程支架材料的要求。

英文摘要：

Porous biocomposites of nano-hydroxyapatite/carboxymethyl chitosan were prepared by means of porogen leaching method and characterized by IR, XRD and SEM. At the same time, the porosity and compressive strength were also tested. In the process, anhydrous ethanol is porogen leaching solvent and citric acid is sticky solvent. The results show that the chemical compositions of the two phases have not changed before and after being compounded, but interactions between them have occurred. The composites show porous structure and the pores are interconnected. The diameter of the pores is about from several microns to six hundred microns and main of them are circular which is profits to the growth and extend of many tissues. When the content of CMCS is 40% and the ratio of composite and porogen is 1 ： 1 the porosity ratio is about 75% and the compressive strength can exceed 21MPa which should be desirable for bone tissue engineering.