中文摘要：

针对放疗过程的摆位误差以及动态肿瘤靶区定位跟踪难题,图像引导精准定位跟踪系统KylinRay-IGRT基于双X射线成像和红外引导,实现了治疗前对病人的摆位,以及治疗过程中对肿瘤运动的跟踪与控制。系统主要包含X射线图像实时采集、多维多模式图像配准和快速实时的红外定位引导等功能。本研究开展基于双X射线成像系统的摆位误差纠正和基于红外信号的定位与呼吸跟踪实验,对系统进行了功能性和正确性测试。结果表明KylinRay-IGRT的定位精度可满足临床需求,为进一步开展自适应放疗关键技术和算法提供研究平台和技术基础。

英文摘要：

Targeting at the setup errors and difficulties in positioning and tracking tumor areas during radiotherapy, imageguided accurate positioning and tracking system Kylin Ray-IGRT which combined dual stereotactic X-ray imaging and infrared tracking techniques is developed to achieve an accurate setup before each fractioned treatment and to track and control the tumor movement during treatment. The main functions of the system include real-time X-ray image acquisition, multimodality image registration and infrared-based tracking. Experiments and simulations, including the correction of setup errors based on dual X-ray imaging system as well as the infrared-based positioning and respiratory tracking experiments based on infrared signal, are carried out to verify the efficiency and accuracy of Kylin Ray-IGRT. The validation results show that the positioning accuracy of Kylin Ray-IGRT meets the clinical requirement, providing an efficient platform and technology base for the further study on adaptive radiotherapy key technologies and algorithms.