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Comparative analysis of lung cancer with features of bronchioloalveolar carcinoma and other types of adenocarcinoma
  • ISSN号:2095-9621
  • 期刊名称:《肿瘤学与转化医学:英文版》
  • 时间:0
  • 分类:R[医药卫生]
  • 作者机构:[1]Department of Pathology, Tianjin Medical Universit Cancer Institute and Hoapital, Tianjin Key Laboratory of Cancer Prevention, [2] Tianjin Diagnosis and Therapy Cancer of Lung Cancer, Tianjin 300060, China
  • 相关基金:Supported by a grant from the National Nature Sciences Foundation of China (No. 30770828).
中文摘要:

这研究的目的是调查 clinicopathologic 和肺腺癌的部分子类型的预示的因素的目的包括纯 bronchioloalveolar 癌(用绳子拖的平底渡船) ,有没有用绳子拖的平底渡船的用绳子拖的平底渡船部件和交流的腺癌(交流) 部件。方法完全被跟随在上面 3 年的 106 个腺癌标本,从在天津医药大学的癌症医院里为病理地证实的肺的腺癌经历了外科的切除术的 106 个病人(45 个男人和 61 个女人) 被获得,从 2004 年 6 月到 2005 年 12 月。根据最近 2004 世界健康组织() 肺癌症的病理学的分类标准,肺腺癌被划分成三亚群:纯用绳子拖的平底渡船,有用绳子拖的平底渡船部件的交流和没有用绳子拖的平底渡船部件的交流。临床的数据回顾地基于统计方法被分析。所有数据用社会科学统计套装软体统计被分析同时,软件和 Kaplan-Meier 幸存曲线被构造我们进行了木头等级测试。统计分析显示出的结果那个不重要的协会在性和年龄在三个组之中被发现;然而,烟索引,肿瘤尺寸, N 阶段, TNM 阶段,手术后的复发和转移在三个组之中有统计上重要的关联(P < 0.01 ) 。三个组的 3 年的幸存率分别地是 96.4% , 61.0% 和 40.5% ,它有统计上重要的差别。并且 3 年的幸存率比在有肺腺癌的另外的类型的病人在有纯用绳子拖的平底渡船的病人是显著地更高的(P < 0.01 ) 。与另外的二个组(有用绳子拖的平底渡船部件的纯用绳子拖的平底渡船和交流) 相对照,我们发现了没有用绳子拖的平底渡船部件的肺腺癌的 3 年的预后比二个前者更坏的证据。三个组(纯用绳子拖的平底渡船,有用绳子拖的平底渡船部件的交流和没有用绳子拖的平底渡船部件的交流) 有他们的自己的不同 clinicopathologic 的结论展示分别地并且完全不同的临床的预后。肺腺癌的子类型的严格的区别能为科学、全面的临床的治疗

英文摘要:

Objective: The aim of this study was to investigate the clinicopathologic and prognostic factors of the partial subtypes of lung adenocarcinoma, including pure bronchioloalveolar carcinoma (BAC), adenocarcinoma (AC) with BAC component and AC without BAC component. Methods: One hundred and six adenocarcinoma specimens which were followed up completely for 3 years, were obtained from 106 patients (45 men and 61 women) who underwent surgical resection for pathologically confirmed pulmonary adenocarcinoma in the Cancer Hospital of Tianjin Medical University, from June 2004 to December 2005. According to the recent 2004 World Health Organization (WHO) pathological classification criteria of lung cancer, lung adenocarcinomas were divided into three subgroups: pure BAC, AC with BAC component and AC without BAC component. The clinical data were retrospectively analyzed based on statistical methods. All data were analyzed using SPSS statistics software and Kaplan-Meier survival curves were constructed, meanwhile, we conducted a Log-rank test. Results: The statistical analysis showed that no significant association was found among the three groups in gender and age; however, smoke index, tumor size, N stage, TNM stage, postoperative recurrence and metastasis had a statistically significant correlation among three groups (P 〈 0.01). The 3-year survival rates of the three groups were 96.4%, 61.0% and 40.5% respectively, which had a statistically significant difference. And the 3-year survival rate was significantly higher in the patients with pure BAC than in the patients with other types of lung adenocarcinomas (P 〈 0.01). In contrast to the other two groups (pure BAC and AC with BAC component), we found the evidence that the 3-year prognosis of lung adenocarcinoma without BAC component was worse than the two formers. Conclusion: The three groups (pure BAC, AC with BAC component and AC without BAC component) have their own distinct clinicopathologic features respectively and com

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期刊信息
  • 《肿瘤学与转化医学:英文版》
  • 主管单位:中华人民共和国教育部
  • 主办单位:华中科技大学同济医学院
  • 主编:陈安民 于世英
  • 地址:武汉解放大道1095号同济医院内
  • 邮编:430030
  • 邮箱:dmedizin@tjh.tjmu.edu.cn
  • 电话:027-83662630/83662645
  • 国际标准刊号:ISSN:2095-9621
  • 国内统一刊号:ISSN:42-1865/R
  • 邮发代号:38-121
  • 获奖情况:
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  • 被引量:0