中文摘要：

中毒性表皮坏死松解症（TEN）是一种急性皮肤炎症反应，属于重型药疹的一类。随着抗生素、非甾体类解热镇痛等药物在救治危重患者中的广泛应用，TEN在临床上，特别是ICU病房中其发病率有增高趋势。TEN病死率较高，且对危重患者的整体预后有较大影响。本文报道南京军区南京总医院普通外科收治的1例重症急性胰腺炎患者，应用阿司匹林预防血栓及栓塞并发症过程中并发TEN，总结该病的诊断和治疗经验以供临床医师参考。

英文摘要：

Toxic epidermal necrolysis （TEN） is an acute skin inflammation, which belongs to heavy drug eruption. With the extensive and widespread use of antibiotics, nonsteroi- dal antipyretic analgesics and other pharmacotherapies in the treatment of critically ill patients, the trend of morbidity of TEN is gradually increased, especially in intensive care unit. In con- sideration of the high mortality rate of TEN and its great influence on the overall prognosis of patients with critical illness, we sum- marized the diagnosis and treatment experiences in the manage- ment of TEN based on retrospective analysis of one patient with severe acute pancreatitis and TEN.