Elf-1是Ets转录因子家族的一员,参与细胞增殖、分化和恶变等生理病理过程.文章对Elf-1与T细胞分化发育、肿瘤及自身免疫性疾病的关系进行综述.
Elf-1 (E74-like factor 1) is a member of Ets transcription factor family,which participated in physiological and pathological process of cells proliferation,differentiation and tumorigenesis. In this review,we summarize that Elf-1 is related to T cell differentiation and development,tumor and autoimmune disease.