生物被膜是菌体在自然界中一种常见的生存状态,直接影响着人类生产和生活的各个方面。枯草芽孢杆菌是重要的工业菌株,同时也是研究生物被膜的模式菌株。本文结合作者目前的研究,综述了目前对枯草芽孢杆菌形成生物被膜研究所取得的重要进展,包括枯草芽孢杆菌形成生物被膜的主要过程、特征、研究模型及分子调控机制,并提出了今后研究的热点问题。
Biofilm is a prevalent lifestyle in nature and closely related to the life and production of humans. Bacillus subtilis is an important industrial strain and a good model for biofilm research. Combined with our current studies, we reviewed significant progress on biofilm formation by Bacillus subtilis, including main process, characteristics of biofilm formation, research models, and regulatory pathway for biofilm formation. In addition, further research focuses are addressed.