中文摘要：

降钙素基因相关肽（CGRP）是一个含37个氨基酸残基的神经肽,对心血管、神经和消化等系统的功能有重要的调节作用。CGRP功能主要由其受体介导。研究发现,CGRP受体由降钙素受体样受体（CRLR）、受体活性修饰蛋白-1（RAMP1）和受体组分蛋白（RCP）组成,不同受体组分在受体的跨膜信号转导中所起的作用存在差异。

英文摘要：

Calcitonin gene-related peptide （CGRP） is a 37 amino acid neuropeptide, which plays an important role in cardiovascular, nervous system and digestive system. The function of CGRP was mediated via the receptor. CGRP receptor consists of at least three proteins： calcitonin receptor like receptor （CRLR）, receptor activity-modifying protein 1 （RAMP1）, and receptor component protein （RCP）. The different functions of three proteins are responsible for the trans-membrane signal transduction of the receptor.