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中文摘要：
DNA折纸术是近年来提出的一种新颖的DNA自组装方法，是DNA纳米技术和DNA自组装领域的重大研究进展之一．与传统的DNA自组装技术不同，DNA折纸术通过一条长的环状单链DNA与一系列预设计的短链DNA片段碱基互补配对，构造出高度复杂的二维纳米图案和三维纳米结构．与传统纳米自组装方法相比，DNA折纸术构造的二维、三维纳米结构，具有更佳的精细程度和可控性，而且其实验条件要求低，操作简单，效率高．将二维或三维DNA折纸纳米结构作为模板，与功能纳米粒子进行组装，能够得到具有特殊性能的纳米器件，因此DNA折纸术在纳米领域具有巨大的潜在应用价值．本文介绍了DNA折纸术在功能复合结构组装方面的研究进展与DNA折纸术的展望．
英文摘要：
As a novel self-assembly method developed in recent years, DNA origami is one of the greatest progress in the field of DNA nanotechnology and DNA self-assembly. Different from traditional DNA self-assembly, DNA origami, on the basis of the hybridization of a long circular genomic single stranded DNA with a group of staple strands, can be used to construct twoor three- dimensional sophisticated shapes at the nanoscale. Moreover, the nanostructures by DNA origami are more predictable, precise, controllable and efficient. The merits also include relatively low requirements for the experimental conditions and operation skills. A variety of functional nanoparticles can be assembled onto the DNA origami nanoscaffolds, to obtain complicate nanodevices with special functions. Therefore, DNA origami has shown great potential in nanotechnology. This review describes the progress of DNA origami in the assembly of diverse DNA nanostructures and the prospect of DNA origami in future.
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