中文摘要：

利用各种色谱技术从树舌灵芝的子实体中分离得到8个化合物,结合波谱学方法鉴定了它们的结构,分别为：shushene A（1）、shushene B（2）、lucidulactone A（3）、2,3-dihydroxy-1-（4-hydroxy-3,5-dimethoxyphenyl）-1-propanone（4）、6-hydroxy-4H-chromen-4-one（5）、1-（4-ethylphenyl）-1,2-ethanediol（6）、1-（2-ethylphenyl）-1,2-ethanediol（7）和吲哚醛（8）。其中化合物1和2是新化合物,化合物3~8系首次从树舌灵芝中获得。化合物1和2是外消旋体,我们对其进行了手性拆分并通过量子化学计算确定了其对映体的绝对构型。此外,还采用ELISA法对化合物1和2的肾保护活性进行了测试。

英文摘要：

Eight compomlds including two new compounds, namely shushenes A （1） and B （2）, were isolated from the fruiting bodies of Ganoderrna applanatum. Their structures were identified by means of spectroscopic methods. The struc- tures of the known compounds are lucidulactone A （ 3 ）, 2,3-dihydroxy-1-（4-hydroxy-3,5-dimethoxyphenyl） -1-propa- none （4）, 6-hydroxy-4H-chromen-4-one （ 5 ）, 1 - （4-ethylphenyl） -1,2-ethanediol （6）, 1- （2-ethylphenyl） -1,2-ethane- diol （7） and indole-3-carboxaldehyde （8）, which were all isolated from this species for the first time. Of note, com- pounds 1 and 2 were isolated as racemic mixtures, chiral separation followed by computational methods allowed their absolute configuration assignment. In addition,inhibition of compounds 1 and 2 on fibronectin expression was tested by using an enzyme-linked immunosorbent assay （EIJSA）.