中文摘要：

包含 4-methyl-1,2,3-thiadiazole 衍生物的一系列新奇 3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy ) 苯基经由 Ugi 反应被设计并且综合。他们的结构被红外， 1H NMR， 13C NMR 和高分辨率的集体光谱学证实。初步的生物鉴定结果显示一些标题混合物在 50 g/mL 举办了好杀真菌剂活动；大多数混合物在 500 g/mL 和 100 g/mL 对烟草马赛克病毒介绍了直接抑制活动，好 inactivation 和药品活动的某个度；一些混合物对 Plutella xylostella L 显示出好 larvicidal 活动。在对在 2 g/mL 的一种蚊虫 pipiens pallens 的 200 g/mL 和优秀 larvicidal 活动。

英文摘要：

A series of novel 3,5-dichloro-4-（1,1,2,2-tetrafluoroethoxy）phenyl containing 4-methyl-l,2,3-thiadiazole derivatives were designed and synthesized via Ugi reaction. Their structures were confirmed by IR, 1H NMR, 13C NMR and high-resolution mass spectroscopy. The preliminary bioassay results indicated that some title compounds had good fungicide activity at 50 ug/mL; most of the compounds presented a certain degree of direct inhibition activity, good inactivation and curative activity against tobacco mosaic virus at 500 ug/mL and 100 ug/mL; some compounds showed good larvicidal activity against Plutella xylostella L. at 200 ug/mL and excellent larvicidal activities against Culex pipiens pallens at 2 ug/mL.