中文摘要：

首先将辛基酚聚氧乙烯醚（OP10）、苯乙烯基酚聚氧乙烯醚（602）和蓖麻油聚氧乙烯（40）醚（EL-40）分别与蓖麻油聚氧乙烯（20）醚（EL-20）复配制备阿维菌素水乳剂,从亲水亲油平衡（HLB）值、临界胶束浓度（cmc）、表面张力等方面分析了二元表面活性剂复配对乳液稳定性的影响;其次,在EL-40与EL-20复配基础上,将苯乙烯基酚聚氧乙烯聚氧丙烯醚（1601）,嵌段共聚物（L64）和辛基酚聚氧乙烯醚磷酸酯（A）分别添加到乳液中,从粒径、表面张力和zeta电势等方面考察三元表面活性剂复配对乳液稳定性的影响.结果表明：EL-40与EL-20复配具有较低的表面张力,可制备较稳定的乳液.添加1601和L64对乳液稳定性有一定提高;而添加A大大提高了乳液的稳定性,这是由于A显著降低了液滴粒径和表面张力,增加了zeta电势.

英文摘要：

The preparation of avermyctin emulsions in water was achieved by mixing the surfactants polyoxyethylene （10） octylphenyl ether （OP10）,polyoxyethylene styrenated phenol ether （602）,and polyoxyethylene （40） castor oil ether （EL-40） with polyoxyethylene （20） castor oil ether （EL-20）,separatively.Emulsion stability was investigated by analyzing the hydrophile-lipophile balance （HLB）,critical micelle concentration （cmc）,and surface tension.Then,the surfactants of polyoxyethylene polyoxypropylene styrenated phenol ether （1601）,block copolymer （L64）,and octyl phenyl polyoxyethylene phosphonate （A） were added to the emulsion made by blending EL-40 and EL-20,separatively.The stability of the emulsions was investigated further and discussed in terms of droplet size,surface tension,and zeta potential.Results showed that the blend of EL-40 and EL-20 resulted in a relatively stable emulsion because of its lower surface tension.The addition of 1601 and L64 improved the stability of the emulsion to some extent,while A greatly enhanced the stability because it markedly decreased the droplet size and the surface tension while increased the zeta potential.