中文摘要：

基于多壁碳纳米管修饰玻碳电极对阿替洛尔的催化作用，建立了测定阿替洛尔的电化学分析方法。多壁碳纳米管修饰玻碳电极与裸玻碳电极相比，显著提高了阿替洛尔的氧化峰电流，降低了氧化峰电位，提高了测定的灵敏度。该电极测定阿替洛尔的线性范围为4．9×10^-6．3×10^-4mol／L，检出限为2×10^-6mol／L。对1．3×10^-4mol／L阿替洛尔进行11次平行测定，相对标准偏差为4．4％。此法可用于阿替洛尔片剂中阿替洛尔的测定。

英文摘要：

Electrochemical behavior of atenolol and its analytical application were investigated at muhi-wall carbon nanotubes （MWNT） modified glassy carbon electrodes （GCE）. An irresivible oxidation peak was observed at 773 mV at a the MWNT/GCE while an irresivible oxidation peak appeared at 1129 mV at bare GCE. The electrochemical response of atenolol was greatly improved at MWNT/GCE, compared with that at the bare GCE. Under optimal conditions, there was a good linear relationship between anodic peak current and atenolol concentration in the range from 4.9 ×10^-6 to 6.3 ×10^-4 mol/L with a detection limit of 2 ×10^-6 mol/L （S/N = 3）. The MWNT/GCE has been applied to the determination of atenolol in drug with good results.