中文摘要：

利用7-（2-羟基乙氧基）-4-甲基香豆素（HEMC）疏水改性透明质酸（HA）制得光敏双亲大分子（HA-HEMC）,并通过自组装形成了HA-HEMC胶体粒子。通过核磁共振氢谱和紫外分光光度计确定了HA-HEMC的结构及取代度;采用动态激光光散射、纳米粒度仪和透射电镜等手段对胶体粒子的性质及形貌进行了表征。进一步以HA-HEMC胶体粒子作为颗粒乳化剂稳定油水界面,研究了胶体粒子质量浓度、油相类型、水相pH和盐浓度对胶体粒子乳化性能的影响。结果表明：HA-HEMC可以在选择性溶剂中自组装形成粒径约为236nm的球形胶体粒子;该胶体粒子能够在较宽的pH范围内（3-11）稳定水包油型乳液且所得乳液有良好的耐盐性;此外,HAHEMC胶体粒子还能稳定多种油-水体系。

英文摘要：

By using 7-（2-hydroxyethoxy）-4-methylcoumarin（HEMC） hydrophobic modified hyaluronic acid （HA）, photosensitive amphiphilic macromolecules （HA-HEMC） were prepared and HA-HEMC colloidal particles were obtained by self assembly. The structure and substitution degree of HA-HEMC were characterized by hydrogen nuclear magnetic spectra and UV-Vis spectrophotometer. The properties and morphologies of HA-HEMC colloidal particles were characterized by dynamic light scattering, nanoparticle size analyzer and transmission electron microscopy. Additionally, HA-HEMC colloidal particles were applied as the particulate emulsifier to stabilize oil- water interface and the emulsification performance of HA-HEMC colloidal particles in different conditions, such as mass concentration of colloidal particles, oil type, pH value and salt concentration in aqueous phase were investigated. Results showed that HA-HEMC were able to form spherical colloidal particles with the average diameter of 263 nm in selective solvent and HA-HEMC colloidal particles could stable oil-in-water Pickering emulsions in the broader range of pH（3^11） and various concentrations of NaCl. In addition,the colloidal particles were able to stabilize variety of oil-water system.