波形蛋白(vimentin)是主要存在于间充质细胞中的一种中间纤维蛋白,近些年研究显示其作为细胞骨架成分,除具有支撑和维持细胞形态的功能外,还参与调节细胞的多种生命活动如:细胞粘附和迁移、信号转导、基因表达和细胞凋亡等。本文就近年来发现的vimentin在细胞中具有的潜在功能进行综述。
Vimentin is an important member of intermediate filament family in mesenchymal cells. Recent advances have shown that vimentin plays important roles in maintaining the shape of the cell, regulating cell adhesion and migration, signaling transduction, gene expression, as well as cell apoptosis. Here, we summarize the progress of the potential function of vimentin in cells.