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中文摘要：
目的：探讨食管碰撞癌的临床病理特点及可能病因。方法：回顾性研究1例食管碰撞癌（小细胞癌伴高分化鳞癌）的临床表现、影像学检查以及病理大体和镜下形态特点，并结合文献复习。结果：本例肿瘤由食管小细胞癌和高分化鳞癌组成，两者独立存在，相邻处由纤维组织分隔；小细胞表达NSE、Syn和CgA等神经内分泌标记，高分化鳞癌则不表达神经内分泌标记，癌组织侵及食管深肌层。确诊后给予手术治疗，6个月后肿瘤远处转移，治疗无效死亡。结论：碰撞癌是一种罕见的恶性肿瘤结合，食管小细胞癌合并高分化鳞癌更为罕见，相关的临床特点有待进一步总结。
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