中文摘要：

分别从手性构型高度稳定的（R）和（S）-2，2＇-二乙炔基-1，1’-联萘模板出发，通过保护基的控制导入、偶联反应、保护基脱去以及分子间偶合成环4个步骤成功地合成了一种具有螺旋结构特征的新的光学活性分子方（Molecular square）——（R，R，R，R）-1和（S，S，S，S）-1．用MS，IR，UV-Vis，^1H和^13C NMR以及元素分析等方法对目标化合物进行了结构表征．测定并分析比较了2个目标化合物的比旋光度[α]D和圆二色性（CD）等光学性质．在CH2Cl2溶液中，异构体（R，R，R，R）-1和（S，S，S，S）-1的[α]0^25值分别为＋887．3°和-889．7°，并且其CD谱表现出对称的镜像特征。

英文摘要：

（R）- and（S）-2,2＇-diethynyl-1,1 ＇-binaphthyl with highly stable chiral configurations were used as the structural templates and linking bridges, and a new type of chiral molecular square with helical structure （ R, R, R, R） -1 and （ S, S, S, S） -1 were synthesized in enantiopure form via four steps including the introduction of protecting-group, intermolecular coupling reaction, removal of protecting group, and intermolecular crosscoupling cyclyzation. Compound 1 was characterized by MS, IR, ^1H and ^13C NMR as well as elemental analysis. The specific rotations（ [α]D^25） of the two isomers in CH2Cl2 are ＋ 887.3° and -889.7°, respectively, and their circular dichroism（CD） spectra represented exactly the mirror images of each other. These results reflected unambiguously enantiomeric relationship between the two isomers.