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超声检测心外膜脂肪组织与颈总动脉内中膜厚度在预测冠心病中的诊断价值
  • ISSN号:1005-9202
  • 期刊名称:《中国老年学杂志》
  • 时间:0
  • 分类:R541[医药卫生—心血管疾病;医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:[1]石河子大学医学院第一附属医院功能科,新疆石河子832008
  • 相关基金:国家自然科学基金(30860102)
中文摘要:

目的探讨心外膜脂肪组织(EAT)与颈总动脉内中膜厚度(CIMT)、冠心病的相关性,进一步分析EAT预测冠心病的意义。方法入选确诊冠心病需行冠脉造影住院患者160例(其中非冠心病86例,冠心病74例),入院后10d内彩超检测EAT厚度、CIMT厚度,分析EAT厚度与CIMT厚度、冠心病的相关性。结果相关性分析显示,EAT厚度与CIMT有较好的相关性(r=0.79,P〈0.001);冠心病组EAT、CIMT较非冠心病组明显高[(8.65±1.45)vs(6.30±1.53)mm;(1.17±0.21)VS(0.83±0.19)mm;均P〈0.01)];CIMT≥0.92mm预测冠一tL,病的敏感度、特异度、Youden指数分别为0.81、0.78、0.59,EAT≥7.24mm预测冠心病的敏感度、特异度分别为0.84、0.80、0.64。结论超声检测EAT和CIMT可作为冠心病的预测指标。‘

英文摘要:

Objective To explore the correlation among epicardial adipose tissue (EAT) , carotid artery intima medial thickeness (CIMT) and coronary heart disease(CAD) , further analyze the significance of EAT to predict CAD. Methods 160 hospitalized patients with CAD underwent coronary angiography were consecutive selected, including 86 cases with non-CAD, 74 cases with CAD, within admis- sion 10 d, the EAT and CIMT thicknesses were measured by color Doppler ultrasound. Results Correlation analysis showed,EAT thickness had good eorrelation with CIMT ( r = O. 79 ;P 〈 0. 001 ). Compared with those of non-CAD group, EAT, CIMT of CAD group were significant- ly higher( (8.65 ± 1.45) vs. (6. 30 ± 1.53) mm; ( 1.17 ±0. 21 ) vs. (0. 83 ±0. 19) ram, P 〈0. 0017. For patients with coronary artery stenosis 〉 50%, the sensitivity, specificity and Youden index of CIMT ≥ 0. 92 mm were 0. 81,0. 78,0. 59, respectively; the sensitivity, spe- cificity and Youden index of EAT ≥ 7.24 mm were 0. 84,0. 80,0, 64, respectively. Conclusions Color Doppler detection of EAT and CI MT may have the Potential to be a oredictor of risk factors for CAD and arteriosclerosis.

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期刊信息
  • 《中国老年学杂志》
  • 北大核心期刊(2011版)
  • 主管单位:中国老年学学会
  • 主办单位:中国老年学学会 吉林省医学期刊社
  • 主编:陈可冀 赵吉光
  • 地址:长春市建政路971号
  • 邮编:130061
  • 邮箱:okgood911@126.com
  • 电话:0431-88923384 88940685
  • 国际标准刊号:ISSN:1005-9202
  • 国内统一刊号:ISSN:22-1241/R
  • 邮发代号:12-74
  • 获奖情况:
  • 第二届北方优秀期刊,吉林省双十佳期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版),中国北大核心期刊(2000版)
  • 被引量:105001