l-脯氨酸催化下,以含有卤原子、不同类型的烷基及烷氨基取代苯甲醛类化合物、苯乙酮和醋酸铵为原料,合成了8个2,6-二苯基-4-芳基取代吡啶化合物,对相关合成条件进行了归纳总结,产物经核磁共振、质谱、红外等进行表征,并进一步进行了初步的抗菌活性测试.
Eight 2,6-diphenyl-4-arylpyridines were synthesized with halogen-,alkyl-and alkylamino-substituted benzaldehydes,acetophenone and ammonium acetate catalyzed by l-proline.The relevant synthetic conditions were summarized,and the products were identified by NMR,ESI-MS and FT-IR analysis.Furtherly,the preliminary antimicrobial activities of these compounds were evaluated.