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中文摘要：
5-乙氧羰基-4-芳基-6-甲基-3，4-二氢嘧啶-2-酮与丁炔二酸二甲酯反应，合成了系列新的噻唑并[3，2-a]嘧啶类化合物，反应具有时间短、收率高、后处理简单等优点．采用NMR（^1H，^13C，COSY,HSQC和HMBC），IR等多种谱学技术，结合元素分析对产物进行详细表征，通过对目标产物的1,3－偶极环加成的衍生化产物进行X射线单晶衍射而确定目标产物的结构．
英文摘要：
A new class of thiazolo[3,2-a]pyrimidine compounds were synthesized by the reaction of 5-carbethoxyl-4-aryl-6-methyl-1,2,3,4-tetrahydropyrimidin-2-ones with dimethyl acetylenedicarboxylate. The reaction has the advantages of excellent yields and simple workup procedures. The products were characterized thoroughly by IR and NMR （^1H, ^13C, COSY, HSQC and HMBC） together with elemental analysis. The X-ray crystallographic analysis of the 1,3-dipolar cycloaddition derivative of the title product provided the direct information for the structure of the product.
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