中文摘要：

以明胶（GE）和阿拉伯胶（AG）为壁材,采用复凝聚法制备昆虫β-蜕皮激素微胶囊。通过正交实验获得微胶囊的最佳制备工艺条件。利用扫描电子显微镜和光学显微镜对β-蜕皮激素微胶囊形貌进行表征。研究了β-蜕皮激素微胶囊的释放行为和光稳定性。结果表明：壁材质量分数为3%,芯壁材质量比为1：1,前期pH值为4.6,后期pH值为8.0为最佳工艺条件。在此条件下,可形成壁膜光滑,大小均匀的球形微胶囊,其平均粒径大小为5μm,载药量与包覆率分别达到68.5%和63.4%。微胶囊能够明显延长蜕皮激素的释放时间及增强蜕皮激素的光稳定性。

英文摘要：

Hydroxyecdysone（β-HE）was encapsulated by complex coacervation with gelatin（GE） and acacia gum（AG）as the wall materials.An orthogonal design was adopted to optimize the preparation procedure of microcapsules.The microcapsules were characterized using optical microscopy and scanning electron microscopy（SEM）,and their in vitro controlled release pattern and photostability were studied.The optimal conditions were as 3% concentration of wall materials with 1：1 core/wall mass ratio at early pH value of 4.6 and terminal pH value of 8.0.Under these conditions,smooth and uniform microcapsules with a mean diameter of 5μm were obtained,the drug loading and encapsulation efficiency of which were 68.5% and 63.4%,respectively.The capsules prolonged the release time of the encapsulated β-HE and enhanced the photostability of β-HE.