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含双官能团杂环配体的有机铋、锑配合物的合成、结构、性质和构效关系研究
  • 项目名称：含双官能团杂环配体的有机铋、锑配合物的合成、结构、性质和构效关系研究
  • 项目类别：面上项目
  • 批准号：20771053
  • 申请代码：B0114
  • 项目来源：国家自然科学基金
  • 研究期限：2008-01-01-2010-12-31
  • 项目负责人：尹汉东
  • 负责人职称：教授
  • 依托单位：聊城大学
  • 批准年度：2007
中文摘要：

采用金属有机化学的知识和方法研究生命科学中的化学问题，已成为当今化学学科的重大前沿领域之一，该领域关系到在分子基础上对生命现象和生命过程的深入认识，对医学和工农业的发展有直接的关系。在金属有机化学研究领域中，具有生物活性的金属有机化合物的合成、结构、性能及构效关系研究引起了人们极大关注。由于有机铋、锑的的特殊生物活性，尤其是有机铋的无毒性、不致癌性以及不存在环境污染等特点，使得有机铋、锑化合物的研究近年来受到人们的重视，呈现出良好的潜在应用前景。为此，我们利用含双官能团杂环配体与有机铋、锑化合物进行反应，合成系列新型金属有机配合物,尤其是含杂环配体的金属有机配位聚合物。深入探索它们的合成方法学，研究其配位结构及抗癌活性，总结其构效关系。既为该类配合物的合理设计提供思路，也为该领域的实际应用提供依据及信息。

中文主题词： 有机铋、锑配合物; 含双官能团杂环配体; 抗癌活性; 构效关系
结论摘要：

英文主题词Organobismuth, organoantimony complexes; bifunctional heterocyclic ligand; anticancer activity; structure-effect relationship

成果综合统计
成果类型
数量
  • 期刊论文
  • 会议论文
  • 专利
  • 获奖
  • 著作
  • 105
  • 40
  • 0
  • 0
  • 0
期刊论文
The first 1D tetranuclear organotin(IV) complex with N '-acylsalicylhydrazide: Synthesis, characteri
Synthesis, characterization and crystal structure of a novel 3D network triorganotin(IV) polymer con
Synthesis, characterizations and crystal structures of new antimony (III) complexes with dithiocarba
Synthesis, spectroscopic and structural aspects of triphenylantimony(V) complex with internally func
Synthesis, characterization and crystal structure of binuclear diorganotin(IV) complexes derived fro
Di-μ3-oxido-bis(μ2-quinaldato-k2O:O)- bis(quinaldato-k2N,O)tetrakis[di-n-butyltin(IV)]
μ-3-Thienylmalonato-κ2O1:O3- bis[triphenyltin(IV)]
Chlorido(2-chloronicotinato) triphenylantimony(V)
Bis(4-aminobenzoato-κO)triphenylantimony(V)
catena-Poly[[(N,N-diethyldithiocarbamato-κ2S:S’)phenylbismuth(III)]-μ-chlorido]
Di-μ-hydroxido-bis[aquatrichloridotin(IV)] diethyl ether disolvate
Bis(5-bromopyridine-2-carboxylato -κO)triphenylantimony(V)
μ-Oxido-bis[(chloroacetato-κO) triphenylantimony(V)]
catena-Poly[[tri-n-butyltin(IV)] -μ-2-thiopheneacetato]
2-[(2-Hydroxy-1- naphthyl)methyleneamino]-1,3-benzothiazole
三苯基锑二茂铁乙酮肟配合物的合成及晶体结构
三甲基锡丙酮酸-2-噻吩甲酰腙的合成及晶体结构
Dichloridotriphenylantimony(V) –bis(pyrrolidin-1-ylthiocarbonyl)disulfide(1/1)
catena-Poly[[trimethyltin(IV)]-μ- quinaldato]
Bis(2-hydroxybenzaldehyde oximato- O)triphenylantimony(V)
Synthesis, characterization and crystal structures of tri- and tetraphenylantimony(V) compounds cont
Synthesis, characterizations and crystal structures of antimony(III) complexes with nitrogen-contain
Synthesis, characterizations and crystal structures of new organoantimony(V) complexes with various
μ-2-Aminoterephthalato-κ2O1:O4-bis[triphenyltin(IV)]
A monoclinic polymorph of (nitrato-κO) tetraphenylantimony(V)
[4-Chloro-N_-(3-methoxy-2- oxidobenzylidene)benzohydrazidato]dimethyltin(IV)
Dimethanolbis[N’- (3-pyridylmethylene)benzohydrazide]sodium(I) iodide
Dichloridooctakis(2-chlorobenzyl)di-μ2-hydroxido-di-μ3-oxido-tetratin(IV)
3-Ethoxy-2-(1,3-thiazol-2-yl)isoindolin-1-one
Tris(O-cyclohexyl dithiocarbonato-κS)antimony(III)
[2-Oxido-1-naphthaldehyde(2-hydroxybenzoyl)hydrazonato]diphenyltin(IV)
μ-Oxido-bis[(2-chloronicotinato-κO) triphenylantimony(V)]
(E )-2-Methoxy-6-(thiazol-2-yliminomethyl)phenol
Bis(5-amino-2-chlorobenzoato-O)triphenylantimony(V)
Octakis(2-chlorobenzyl)di-l2-hydroxidodi-3-oxido-bis(2-phenylacetato)tetratin(IV)
3-Phenyltetrahydrofuran-2,5-dione
catena-Poly[[trimethyltin (IV)] –μ-2,5-difluorobenzoato-κ2O:O’]
catena-Poly [[trimethyltin(IV)] -μ-2,4,6-trichlorobenzoato]
二维网状有机锑对氨基苯乙酸酯的合成、表征及晶体结构研究
catena-Poly[[triphenyltin(IV)]-mu-2-(2-picolinoylhydrazono)propanoato-ka ppa O-2(1):O-2]
[2-Oxido-1-naphthaldehyde (2-hydroxybenzoyl)hydrazonato]diphenyltin(IV)
mu-2-Aminoterephthalato-kappa O-2(1):O-4-bis[triphenyltin(IV)]
(E)-2-Methoxy-6-(thiazol-2-ylimino-methyl)phenol
Octabutylbis{(E)-2-[4-(2-hydroxybenzylideneamino)phenyl]acetato}di-mu(2) -methoxo-di-mu(3)-oxido-tet
制备条件对磷化钼加氢脱硫催化活性的影响
溶胶-凝胶法制备MoP/SiO2催化剂加氢脱硫催化活性的研究
壳聚糖铜催化剂催化H2O2分解反应的研究
N '-[(E)-3-Pyridylmethylidene]benzohydrazide
catena- Poly[[trimethyltin(IV)]-μ-2-(3-thienyl)acetato]
Bis(2-hydroxybenzaldehyde oximato-kappa O)triphenylantimony(V)
溶胶-凝胶法制备MoP/SiO2催化剂及其加氢脱硫催化活性的研究
Bis(2-amino-4-chlorobenzoato)triphenylantimony(V)
SiO2负载壳聚糖席夫碱钯催化剂催化芳香醛酮还原为芳香烃
Bis(5-amino-2-chlorobenzoato-kappa O)triphenylantimony(V)
2,2 '-[Pyridine-2,6-diylbis(carbonylhydrazono)]dipropanoic acid N,N-dimethylformamide disolvate
二甲基锡双2-羟基-1-萘甲醛对苯二甲酰腙配合物的合成及晶体结构
活性炭负载P - Mo - W 杂多酸催化苯酚氧化溴化反应
一维链状有机锡化合物三甲基锡2-喹啉甲酸酯的合成及晶体结构
3-[(3-Oxo-1,3-dihydroisobenzofuran-1-yl)amino]benzoic acid
catena-Poly[[trimethyltin(IV)]-μ-2-(2-chlorophenyl)acetato]
Octabutylbis{(E)-2-[4-(2-hydroxybenzylideneamino)phenyl] acetato}di-μ2-methoxo -di-μ3-oxido-tetratin
N’-[(E )-3-Pyridylmethylidene]benzohydrazide
catena-Poly[[triphenyltin(IV)]-μ-2-(2-picolinoylhydrazono)propanoato-κ2O1:O2]
2,2‘-[Pyridine-2,6- diylbis(carbonylhydrazono)]dipropanoic acid N,N-dimethylformamide disolvate
3, 3’ -Oxybi[isobenzofuran-1(3H)-one]
(E )-2-(Isonicotinoylhydrazonomethyl)benzoic acid methanol monosolvate
Synthesis, Characterization and Crystal Structure of a Trinuclear Diorganotin(IV) Complex with N?-ac
Dibenzothiophene hydrodesulfurization over MoP/SiO2 catalyst prepared with sol-gel method
Octakis(2-chlorobenzyl)di-mu(2)-hydroxidodi-mu(3)-oxido-bis(2-phenylacet ato)tetratin(IV)
Hydrogenation of Aromatic Ketones to Aromatic Hydrocarbons over SiO2-Supported Chitosan Schiff-Base
溶胶-凝胶法制备负载磷钼杂多酸铵催化苯硝化反应
Cyclotrimeric and weakly-bridged cyclotetrameric organotin(IV) compounds assembled from 5-hydroxyiso
Synthesis and structural characterization of organotin(IV) compounds derived from the self-assembly
New organoantimony complexes with the isomers of chlorophenylacetic acid: Syntheses, characterizatio
Synthesis, Characterization, and Crystal Structure of Dinuclear Diorganotin(IV) Complexes Derived fr
Synthesis, crystal structures and spectral characterization of diorganotin compounds with phenylglyo
二丁基锡邻香草醛-2-噻吩甲酰腙的合成及晶体结构
2-(Ethoxycarbonyl)quinolinium butyltrichlorido(quinoline-2-carboxylato-κ2N,O)stannate(IV)
Triphenylbis(2,4,5-trifluoro -3-methoxybenzoato)antimony(V)
Dichloridooctakis(2-chlorobenzyl)di-mu(2)-hydroxido-di-mu(3)-oxido-tetra tin(IV)
二苯基锡水杨醛-2-噻吩甲酰腙的合成及晶体结构
双核二丁基锡双2-羟基-3-甲氧基苯甲醛对苯二甲酰腙配合物的合成及晶体结构
三维结构二苯基锡2，6-吡啶二羧酸酯的合成及晶体结构
负载磷钨酸铵的溶胶-凝胶法制备及催化苯硝化反应的研究
活性炭负载P—Mo—W杂多酸催化苯酚氧化溴化反应
有机锡（Ⅳ）配合物{[（n-C_4H_9）_2Sn（0.5·O_2CC_（12）H_（10）N）（0.5·CH_3O）]_2O}_2的合成、表征和晶体结构
负载磷钨酸铵催化苯硝化反应的研究
会议论文
Synthesis and structure of a new tetranuclear diorganotin(IV) carboxylates
A novel 2D triphenylantimony complex with 4-chlorophenylacetic acid
苯甲酰甲酸4-吡啶酰腙二甲基二氯化锡的合成、表征及晶体结构研究
Synthesis and structure of a new hexameric drum shaped organotin(Ⅳ)complex
Synthesis ,Structure of Diorganotin(IV) complex with Schiff base ligand phenylglyoxylic acid 3-hydro
苯甲酰甲酸草二酰腙二丁基锡的合成、表征及晶体结构研究
Synthesis and structure of a new diphenylantimony carboxylate derivative
Synthesis, Crystal Structure and Antitumor activity of a new tetranuclear antimony(V) complex
一种新型有机锡Schiff碱配合物的合成、晶体结构及抗癌活性研究
Synthesis,crystal structure and anticancer activity of a 26-membered dinuclear macrocycle organotin
邻香草醛缩氨基硫脲类二烃基锡化合物的合成、表征及其超分子结构
Synthesis and crystal structure of a one-dimension chain of bistriphenylantimony(VII) bridged by oxy
Triphenylantimony(V) derivative of oxyge bridged hexa(orgno)di- antimony compound:μ-oxo-bis [2-chlor
Self-assembly of triorganotin(IV) moieties and 3-thiophenemalonic acid: Synthesis, characterization
Synthesis and structures of two novel organoantimony(V) derivatives containing Schiff base ligands
Tetraphenylantimony compound with 2,4-Difluoromandelic acid
一种双锡核二烃基锡Schiff碱化合物的合成、表征、晶体结构及生物活性研究
Synthesis, characterization of the coordination compound (C2H10N2)CoCl4(C2H10N2Cl2)
一种单丁基锡Schiff碱配合物的合成、表征、及晶体结构研究
一维链状二甲基锡异羟肟酸化合物的合成、表征及晶体结构研究
Diorganotin(IV) complex with Schiff base ligand phenylglyoxylic acid 3-hydroxy-2-naphthoic acid hydr
三维网状三苯基锑肟化合物的合成、表征及晶体结构研究
Synthesis and Characterization of dibutyltin oxide(Ⅳ) Compounds [R2SnO(HO-C6H4CONHN=CH-(C6H4)COO)] a
Triphenylantimony complex with salicylaldoxime
The synthesis and characterization of Triphenylantimony compounds
Synthesis and Crystal Structure of a new triphenylantimony(V) complex with 1D extended chain structu
structural characterization and in vitro antitumor activities of some organoantimony(Ⅴ) carboxylate
Synthesis, Crystal Structure and Antimicrobial activity of a new 5-fold ladder complex containing ti
二维网状四苯基锑苯甲酸配合物的合成、晶体结构及抗癌活性研究
Synthesis, crystal structures and in vitro antitumor activities of two novel diorganotin(IV) complex
一维链状四苯基锑苯甲酸化合物的合成、表征及晶体结构研究
新型直线三核2,6-吡啶双酰腙类二烃基锡化合物的合成、表征及晶体结构
Synthesis and Crystal Structure of a novel triphenylantimony(V) complex with two-dimension network s
三苯基锑羧酸配合物的合成，晶体结构及生物活性研究
Synthesis and crystal structure of （ N,N-diethylcarbamto-k2S,S’ ） phenylbismuth(III) chlorid
Synthesis, characterization and crystal structure of a novel complex tetraphenylantimony(V) carboxyl
四苯基锑碳酸配合物的合成，及晶体结构表征
Triphenylantimony complexe with 2-chloropyridinecarboxylic acid
三苯基锡3，5-二羧基吡唑配合物的合成及晶体结构表征
Synthesis and crystal structure of bis(2-thiopheneic-acid) triphenylbismuth(V)
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