中文摘要：

目的分析江苏省启东市1993—2012年间胆囊恶性肿瘤的发病情况。方法整理启东市肿瘤登记系统1993年1月至2012年12月启东市户籍人群胆囊恶性肿瘤发病资料,应用年均变化百分比（APC）模型分析胆囊恶性肿瘤的发病率和标化发病率的时间变化趋势,采用2000年第五次全国人口普查的标准人口年龄构成进行标化。结果 1993—2012年胆囊恶性肿瘤新发病493例,占同期新发恶性肿瘤的0.81%。胆囊恶性肿瘤粗发病率为2.41/10万,标化发病率为1.42/10万。胆囊恶性肿瘤的粗发病率及标化发病率逐年增长（APC=12.83及APC=12.04）。其中女性粗发病率增长速度高于男性（APC=14.51及APC=10.60）。65岁及以上老年人群是胆囊恶性肿瘤的高发人群,占所有发病者的63.49%。结论 1993—2012年启东市人群胆囊恶性肿瘤发病率逐年上升,女性增长速度高于男性。

英文摘要：

Objective To analyze the incidence of gallbladder cancer in Qidong City from 1993 to2012. Methods The clinical data of gallbladder cancer from January 1993 to December 2012 for patients with census registration in Qidong were sorted out from the cancer registration center in Qidong.Annual percent change（ APC） models were applied to describe the annual percent changes of disease incidence and the standardized incidence trend over time. The incidence was standardized with the age structure of standard population from a national census taken in 2000. Results A total of 493 new cases were diagnosed from 1993 to 2012,occupying 0. 81% of new-onset malignant tumors for the same period.The crude incidence rate of gallbladder cancer was 2. 41 /100 000 population and the standardized incidence thereof was 1. 42 /100 000 population. Both the crude incidence and the standardized incidence thereof increased on a yearly basis from 1993 to 2012（ APC = 12. 83; APC = 12. 04） while the annual crude incidence thereof for females increased faster than that for males（ APC = 14. 51; APC = 10. 60）.Old people aged 65 years and above were a high-risk group for gallbladder cancer,occupying 63. 49% of the incidence thereof for all ages. Conclusion The incidence of gallbladder cancer increases in Qidong,Jiangsu province of China on a yearly basis from 1993 to 2012,with the incidence thereof for females increasing faster than that for males.