中文摘要：

目的探讨绒毛膜羊膜炎的相关发病因素及其对新生儿结局的影响和处理对策。方法回顾性分析83例绒毛膜羊膜炎的产妇（观察组）和同期排除绒毛膜羊膜炎产妇142例（对照组）的一般资料,分析孕期影响因素,统计母婴并发症。结果两组孕产妇在围产期保健、孕20周前访视、胎膜早破、死胎发生率方面差异有显著性（P〈0.05）;两组胎儿的出生孕周、出生体重差异无统计学意义（P〉0.05）,Apgar评分、早产率、低体重率差异有统计学意义（P〈0.05）。观察组比对照组更易出现血糖不稳定及心、脑损伤（P〈0.05）。结论胎膜早破易引起绒毛膜羊膜炎,不利于妊娠结局;建议加强孕产期保健宣传,提倡孕期访视及正规产检。

英文摘要：

Objective To examine the influence pathogenic factors causing and its effects on neonatal outcome and countermeasures for coping the disease. Method The clinical data of 83 pregnant women（ as the experimental group） with chorioamnionitis and the clinical data of 142 pregnant women（ chosen as the control group） diagnosed to bear no chorioamnionitis were reviewed.. The influence factors during pregnancy and maternal and infant complications were compared between the two groups. Findings The perinatal care,interview conducted in the 20 weeks of pregnancy,premature rupture of membrane,and stillbirth of the experimental group were significantly different than those for the control group（ P〈0. 05）. No significant difference in gestational week and birth weight was found between the two groups（ P〈0. 05）. Significant difference in Apgar scores,preterm birth rate and low birth weight rate was found between the two groups（ P〈0. 05）. The experimental group were more likely to experience unstable blood sugar,and heart and brain damage. Conclusion Premature rupture of membrane can easily cause Chorioamnionitis. It can bring about unfavorable pregnancy outcome. We propose to strengthen the publicity of perinatal health care and advocate pregnancy interview and formal examination.