中文摘要：

克隆与人遗传病相关的（CCCT）n·（CACC）n重复序列．通过化学合成重复序列及两侧接头序列，两侧接头有EcoR Ⅰ，BamH Ⅰ和Ple Ⅰ酶切位点，EcoRⅠ，BamHⅠ位点用于将重复序列插入pUC18制成的载体，PleⅠ酶切位点可方便地将重复序列从重组质粒中取出．为进一步研究和人遗传病相关的重复序列的结构特性及该类遗传疾病的分子机理奠定基础．

英文摘要：

（GC CT） n · （CAGC）n repeat sequences associated with human genetic diseases were cloned. There exist EcoR Ⅰ, BamH Ⅰand Pie Ⅰsites in chemically synthesized repeat sequences and adaptors .The sites of EcoR Ⅰand BamH Ⅰ were used to insert repeats sequences into vector made from pUC18, while Pie Ⅰ sites can be used to take out repeat sequences from recombined plasmid easily. This work was the basis of the further investigation on structural feature of repeat sequences and molecular mechanism of this kind of genetic diseases.