在老鼠上通过针灸效果的全面评估学习 acupoint 特性的目的与中间的服的动脉吸藏(MCAO ) 当模特儿。由 Zea-longas 线结扎的复制 MCAO 模型被 Zausingers 六点的方法估计的方法,和有 13 个分数的老鼠被选择被组织。根据使随机化并且控制的原则,老鼠被划分成 6 个基本控制组(包括正常的组,假冒的组,模型控制组,没有干预的模型组, Nimodipine 组, lateral-to-Renzhong 组)并且 6 个针灸组[包括 Neiguan ( PC6 )组, Weizhong ( BL40 )组, Chize ( LU5 )组, Sanyinjiao ( SP6 )组, Renzhong ( DU6 )组和 non-acupoint 组织];在每 acupoint 或 non-acupoint, 9 不同参数联合被直角的交叉方法分别地放。有在总数 60 组的,并且每个组有 12 只老鼠。老鼠被针灸与插入电梯的操作对待每 12 h,在总数 6 次。neurobehavioral 分数,服的血流动,梗塞率, microcirculation,和轻显微镜的索引,等等被测量。为了包括地评估针灸,完成研究 acupoint 的特性,簇分析为根据全面评估模型的意见计算的样品的全面效果分数与 SPSS17.0 被做,然后排序并且分类为全面效果分数被做。在针灸组的结果每 acupoint 由于不同针灸参数联合有不同治疗学的效果;在针灸组之中,药品效果的订单作为追随者:Neiguan 组具有非凡的结果, Weizhong 组和 Sanyinjiao 组具有在上面的水平, Chize 组和 Renzhong 组的有效结果具有在底层的有效结果,并且 non-acupoint 组具有无效结果;acupoint 组的治疗学的结果比 non-acupoint 组优异;并且针灸组的药品效果比基本控制组也优异。acupoint 有针灸效果的特性的结论,和 acupoint 特性是相对的。
Objectives: To study the acupoint specificity through the comprehensive evaluation of the acupuncture effect on rat model with the middle cerebral artery occlusion (MCAO). Methods: Duplicated MCAO model by Zea-longa's thread ligation was assessed by Zausinger's six-point method, and rats with 1-3 scores were chosen to be grouped. According to the randomized and controlled principle, rats were divided into 6 basic control groups (including normal group, sham group, model control group, model group without intervention, Nimodipine group, lateral-to-Renzhong group) and 6 acupuncture groups [including Neiguan (PC6) group, Weizhong (BL40) group, Chize (LU5) group, Sanyinjiao (SP6) group, Renzhong (DU6) group and non-acupoint group]; in each acupoint or non-acupoint 9 different parameter combinations were respectively set by orthogonal intersection method. There were in total 60 groups, and each group had 12 rats. The rats were treated by acupuncture with the lifting-thrusting manipulation every 12 h, in total 6 times. Indices of neurobehavioral scores, cerebral blood flow, infarction rate, microcirculation, and light microscope, etc. were measured. In order to comprehensively evaluate the acupuncture effect to research the specificity of acupoint, a cluster analysis was made with SPSS17.0 for the comprehensive effect scores of the samples computed according to the comprehensive evaluation models, and then sorting and classification were made for the comprehensive effect scores. Results: In the acupuncture groups every acupoint had different therapeutic effect due to different acupuncture parameter combinations; among the acupuncture groups the orders of curative effect were as followings: Neiguan group was of exceptional result, Weizhong group and Sanyinjiao group were of valid results in upper level, Chize group and Renzhong group were of valid results in lower level, and non-acupoint group was of invalid result; the therapeutic result of acupoint group was superior to non-acup