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Study on Acupuncture Parameters Impacting on the Acupuncture Effect Using Cluster Analysis in A Rat Model with Middle Cerebral Artery Occlusion
  • ISSN号:0255-2930
  • 期刊名称:《中国针灸》
  • 时间:0
  • 分类:S853.61[农业科学—临床兽医学;农业科学—兽医学;农业科学—畜牧兽医] S858.966[农业科学—临床兽医学;农业科学—兽医学;农业科学—畜牧兽医]
  • 作者机构:[1]First Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin (300193), China, [2]Critical Research Room of Encephalopathy Acupuncture Therapy, Tianjin (300193), China, [3]Class Ⅲ Laboratory of Acupuncture Quantity-Effect Relationship Affiliated to the State, Administration of Traditional Chinese Medicine, Tianjin (300193), China, [4]Moxibustion College of Jiangxi University of Traditional Chinese Medicine, Nanchang (330006), China, [5]Mathematics College of Tianjin Polytechnic University, Tianjin (300387), China, [6]Tianjin Key Laboratory of Acupuncture and Moxibustion Science, Tianjin (300193), China
  • 相关基金:Supported by the Development Plan of National Critical and Basic Research (No. 2012CB518505, 2010CB530500, and 2006CB504504)
中文摘要:

目的将与中间的服的动脉吸藏(MCAO ) 在 Wistar 老鼠模型通过簇分析在针灸效果上调查针灸参数的影响。方法由 Zea-longas 线结扎复制了 MCAO 模型并且选择了老鼠, 13 个分数由要组织的 Zausingers 一百二十方法估计了。老鼠被划分成 6 个基本控制组[(包括一个正常的组,一个假冒的组,一个模型控制组,没有干预的一个模型组,一个 Nimodipine 组,一个 lateral-to-Renzhong ( DU6 )组]并且 6 个针灸组[一个 Neiguan ( PC6 )组,一 Weizhong ( BL40 )组,一个 Sanyinjiao ( SP6 )组,一个 Chize ( LU5 )组,一个 Renzhong ( DU6 )组和 Feixue ( non-acupoint )组]。在针灸组,为每 acupoint 或刺破的地点, 9 个不同参数[ 2 个因素(频率和时间)和 3 个层次(频率的 180 , 120 ,和 60 cpm 并且 5 , 60 ,并且时间的 180 s )]被直角的交叉方法分别地放,在总数 54 组。老鼠被针灸与插入电梯的操作对待一次每 12 h,在总数 6 次。Neurobehavioral 分数,服的血流动,梗塞率, microcirculation,轻显微镜学,等等被测量。因素分析首先被使用在针灸组然后簇分析被哪个用 SPSS17.0 的统计软件做得到样品的全面效果分数。Neiguan (PC6 ) 组,的结果针灸的非凡的结果全面效果是参数 7, 8, 9, 10;有效结果是参数 2, 3, 4,并且病人是参数 5, 6。为 Weizhong (BL40 ) 组,非凡的结果是参数 2, 4;有效结果是参数 3, 5, 6, 7,并且病人是参数 8, 9, 10。为 Chize (LU5 ) 组,非凡的结果是参数 7, 8;有效结果是参数 3, 4, 5, 6, 9, 10;并且病人是参数 2。为 Sanyinjiao (SP6 ) 组,非凡的结果是参数 4, 6;有效结果是参数 2, 3, 5;并且病人是参数 7, 8, 9,10。为 Renzhong (DU6 ) 组,非凡的结果是参数 3, 4, 6, 7, 9, 10;有效结果是参数 2, 5;并且病人是参数 8。为 Non-acupoint 组,非凡的结果是参数 10;有效结果是参数 2,

英文摘要:

Objective: To investigate the influence of acupuncture parameters on the acupuncture effect through the cluster analysis in Wistar rat model with middle cerebral artery occlusion (MCAO). Methods: Duplicated MCAO models by Zea-longa's thread ligation and chose rats with 1-3 scores assessed by Zausinger's six-score method to be grouped. The rats were divided into 6 basic control groups [(including a normal group, a sham group, a model control group, a model group without intervention, a Nimodipine group, a lateral-to-Renzhong (DU6) group] and 6 acupuncture groups [a Neiguan (PC6) group, a Weizhong (BL40) group, a Sanyinjiao (SP6) group, a Chize (LU5) group, a Renzhong (DU6) group and a Feixue (non-acupoint) group]. In the acupuncture groups, for every acupoint or needling site, 9 different parameters [2 factors (frequency and time) and 3 levels (180, 120, and 60 cpm of the frequency and 5, 60, and 180 s of the time)] were set respectively by the orthogonal intersection method, in total 54 groups. The rats were treated by acupuncture with a lifting-thrusting manipulation once every 12 h, in total 6 times. Neurobehavioral scores, cerebral blood flow, infarction rate, microcirculation, light microscopy, etc. were measured. The factor analysis was first applied to get the comprehensive effect scores of the samples in the acupuncture groups and then by which the cluster analysis was made with the statistical software of SPSS17.0. Results: For the Neiguan (PC6) group, the exceptional results of acupuncture comprehensive effect were parameters 7, 8, 9, 10; the valid results were parameters 2, 3, 4, and the invalid were parameters 5, 6. For the Weizhong (BL40) group, the exceptional results were parameters 2, 4; the valid results were parameters 3, 5, 6, 7, and the invalid were parameters 8, 9, 10. For the Chize (LU5) group, the exceptional results were parameters 7, 8; the valid results were parameters 3, 4, 5, 6, 9, 10; and the invalid was parameter 2. For t

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期刊信息
  • 《中国针灸》
  • 北大核心期刊(2011版)
  • 主管单位:中国科学技术学会
  • 主办单位:中国针灸学会 中国中医研究院针灸研究所
  • 主编:刘保延
  • 地址:北京东直门内南小街16号
  • 邮编:100700
  • 邮箱:zgzjzz@sina.com
  • 电话:010-84014411-2946 84014607
  • 国际标准刊号:ISSN:0255-2930
  • 国内统一刊号:ISSN:11-2024/R
  • 邮发代号:2-53
  • 获奖情况:
  • 获国家中医药管理局优秀中医药科技期刊二等奖、一等奖
  • 国内外数据库收录:
  • 美国化学文摘(网络版),波兰哥白尼索引,荷兰文摘与引文数据库,美国生物医学检索系统,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版),中国北大核心期刊(2000版)
  • 被引量:39942