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微生物转化人参皂苷Rb1为稀有皂苷F2
  • 期刊名称:延边大学农学学报 33(2): 112-116 (2011).
  • 时间:0
  • 分类:S567.51[农业科学—中草药栽培;农业科学—作物学]
  • 作者机构:[1]延边大学长白山生物资源与功能分子教育部重点实验室,133002
  • 相关基金:国家自然科学基金(20862017).
  • 相关项目:微生物转化长白山人参主皂苷为抗肿瘤皂苷的研究
中文摘要:

人参皂苷是人参属植物的主要组成成分,具有药理和生物活性.实验发现从土壤中筛选到的菌株CG2具有很高的β-葡萄糖苷酶活性,可以有效地将三七总皂苷转化为次级代谢物,并提出了生物转化途径.经形态学和16S rDNA基因序列分析,属于巨型芽孢杆菌属.

英文摘要:

Ginsenosides which have the pharmacology effects and biological activities have been regarded as the principal components of ginseng genus. Found CG2 isolated from soil, which have a higher β-glucosidase activity can convert ginsenoside notoginsenosides efficiently to less polar metabolites. Also the biotransformation pathway was proposed. As Blast results of 16S rDNA gene sequence of the strain CG2 established, the strain CG2 belongs to a giant Bacillus megaterium.

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